Carbamylation inhibits the ferroxidase activity of caeruloplasmin

The ferroxidase activity of caeruloplasmin (EC 1.16.3.1) is an important antioxidant defence mechanism in man. In chronic renal failure proteins become carbamylated as a result of reactions with urea-derived cyanate. We have therefore investigated the effects of carbamylation on the ferroxidase acti...

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Veröffentlicht in:Biochemical and biophysical research communications 1995-09, Vol.214 (3), p.1073-1078
Hauptverfasser: Roxborough, H E, Millar, C A, McEneny, J, Young, I S
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Sprache:eng
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