Protein malnutrition in pediatric patients with oncologic diseases
To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. In 9 children at least 3 of the 4 rapid-turnover proteins were...
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| Veröffentlicht in: | Klinische Pädiatrie 1987-03, Vol.199 (2), p.73-76 |
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| container_title | Klinische Pädiatrie |
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| creator | Howanietz, H Thun-Hohenstein, L Haschke, F Pietschnig, B Bruckner, R Camaya, Z Jürgenssen, O A |
| description | To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. In 9 children at least 3 of the 4 rapid-turnover proteins were below the age-specific reference values. 7 patients (44%) with low rapid turnover proteins were free from infection, liver and renal dysfunction and thus, diagnosis of protein-caloric malnutrition was established. Anthropometric parameters as weight for age and the weight/height ratio did not predict protein-caloric malnutrition. Nutritional therapy (enteral, parenteral) during a period of 2 weeks resulted in significant increase of albumin (p less than 0.05), prealbumin (p less than 0.01) and retinol-binding protein (p less than 0.01). Rapid turnover proteins can be easily measured in each laboratory and are useful in diagnosis and treatment of protein-caloric malnutrition of children with malignant diseases as long as the limitations of this method are not neglected. |
| format | Article |
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In 9 children at least 3 of the 4 rapid-turnover proteins were below the age-specific reference values. 7 patients (44%) with low rapid turnover proteins were free from infection, liver and renal dysfunction and thus, diagnosis of protein-caloric malnutrition was established. Anthropometric parameters as weight for age and the weight/height ratio did not predict protein-caloric malnutrition. Nutritional therapy (enteral, parenteral) during a period of 2 weeks resulted in significant increase of albumin (p less than 0.05), prealbumin (p less than 0.01) and retinol-binding protein (p less than 0.01). Rapid turnover proteins can be easily measured in each laboratory and are useful in diagnosis and treatment of protein-caloric malnutrition of children with malignant diseases as long as the limitations of this method are not neglected.</description><identifier>ISSN: 0300-8630</identifier><identifier>PMID: 3108568</identifier><language>ger</language><publisher>Germany</publisher><subject>Adolescent ; Adult ; Blood Proteins - metabolism ; Child ; Child, Preschool ; Enteral Nutrition ; Humans ; Neoplasm Recurrence, Local - complications ; Neoplasms - complications ; Parenteral Nutrition ; Prealbumin - metabolism ; Protein-Energy Malnutrition - blood ; Protein-Energy Malnutrition - diagnosis ; Protein-Energy Malnutrition - therapy ; Retinol-Binding Proteins - metabolism ; Serum Albumin - metabolism ; Transferrin - metabolism</subject><ispartof>Klinische Pädiatrie, 1987-03, Vol.199 (2), p.73-76</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3108568$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Howanietz, H</creatorcontrib><creatorcontrib>Thun-Hohenstein, L</creatorcontrib><creatorcontrib>Haschke, F</creatorcontrib><creatorcontrib>Pietschnig, B</creatorcontrib><creatorcontrib>Bruckner, R</creatorcontrib><creatorcontrib>Camaya, Z</creatorcontrib><creatorcontrib>Jürgenssen, O A</creatorcontrib><title>Protein malnutrition in pediatric patients with oncologic diseases</title><title>Klinische Pädiatrie</title><addtitle>Klin Padiatr</addtitle><description>To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. In 9 children at least 3 of the 4 rapid-turnover proteins were below the age-specific reference values. 7 patients (44%) with low rapid turnover proteins were free from infection, liver and renal dysfunction and thus, diagnosis of protein-caloric malnutrition was established. Anthropometric parameters as weight for age and the weight/height ratio did not predict protein-caloric malnutrition. Nutritional therapy (enteral, parenteral) during a period of 2 weeks resulted in significant increase of albumin (p less than 0.05), prealbumin (p less than 0.01) and retinol-binding protein (p less than 0.01). Rapid turnover proteins can be easily measured in each laboratory and are useful in diagnosis and treatment of protein-caloric malnutrition of children with malignant diseases as long as the limitations of this method are not neglected.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Blood Proteins - metabolism</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Enteral Nutrition</subject><subject>Humans</subject><subject>Neoplasm Recurrence, Local - complications</subject><subject>Neoplasms - complications</subject><subject>Parenteral Nutrition</subject><subject>Prealbumin - metabolism</subject><subject>Protein-Energy Malnutrition - blood</subject><subject>Protein-Energy Malnutrition - diagnosis</subject><subject>Protein-Energy Malnutrition - therapy</subject><subject>Retinol-Binding Proteins - metabolism</subject><subject>Serum Albumin - metabolism</subject><subject>Transferrin - metabolism</subject><issn>0300-8630</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotj01LxDAYhHNQ1nX1Jwg9eSu8bdp8HHXxY2FBD3svb5O3u5E2qU2K-O8t2NMww8MMc8W2wAFyJTjcsNsYvwCKSoPesA0vQNVCbdnz5xQSOZ8N2Ps5TS654LPFj2QdLt5kIyZHPsXsx6VLFrwJfTgvuXWRMFK8Y9cd9pHuV92x0-vLaf-eHz_eDvunYz7WXOW8bMEKXZkCOi1IWgtkteDIOyzIKGytNBUYU5em7YQSqtSlBYlVSa2whu_Y43_tOIXvmWJqBhcN9T16CnNspKyXHSkW8GEF53Yg24yTG3D6bdbP_A9w0VM6</recordid><startdate>198703</startdate><enddate>198703</enddate><creator>Howanietz, H</creator><creator>Thun-Hohenstein, L</creator><creator>Haschke, F</creator><creator>Pietschnig, B</creator><creator>Bruckner, R</creator><creator>Camaya, Z</creator><creator>Jürgenssen, O A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198703</creationdate><title>Protein malnutrition in pediatric patients with oncologic diseases</title><author>Howanietz, H ; Thun-Hohenstein, L ; Haschke, F ; Pietschnig, B ; Bruckner, R ; Camaya, Z ; Jürgenssen, O A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p538-32b0d694c10f96e7dd0ed963a3fa1ec8abd7c40cc52cbf6868292d07a42eb6dc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>ger</language><creationdate>1987</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Blood Proteins - metabolism</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Enteral Nutrition</topic><topic>Humans</topic><topic>Neoplasm Recurrence, Local - complications</topic><topic>Neoplasms - complications</topic><topic>Parenteral Nutrition</topic><topic>Prealbumin - metabolism</topic><topic>Protein-Energy Malnutrition - blood</topic><topic>Protein-Energy Malnutrition - diagnosis</topic><topic>Protein-Energy Malnutrition - therapy</topic><topic>Retinol-Binding Proteins - metabolism</topic><topic>Serum Albumin - metabolism</topic><topic>Transferrin - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Howanietz, H</creatorcontrib><creatorcontrib>Thun-Hohenstein, L</creatorcontrib><creatorcontrib>Haschke, F</creatorcontrib><creatorcontrib>Pietschnig, B</creatorcontrib><creatorcontrib>Bruckner, R</creatorcontrib><creatorcontrib>Camaya, Z</creatorcontrib><creatorcontrib>Jürgenssen, O A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Klinische Pädiatrie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Howanietz, H</au><au>Thun-Hohenstein, L</au><au>Haschke, F</au><au>Pietschnig, B</au><au>Bruckner, R</au><au>Camaya, Z</au><au>Jürgenssen, O A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Protein malnutrition in pediatric patients with oncologic diseases</atitle><jtitle>Klinische Pädiatrie</jtitle><addtitle>Klin Padiatr</addtitle><date>1987-03</date><risdate>1987</risdate><volume>199</volume><issue>2</issue><spage>73</spage><epage>76</epage><pages>73-76</pages><issn>0300-8630</issn><abstract>To study the frequency of protein-caloric malnutrition in children (n = 16) with malignant diseases, we measured serum-albumin, -transferrin, -prealbumin and -retinol-binding protein (Radial immunodiffusion) before treatment was started. 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| identifier | ISSN: 0300-8630 |
| ispartof | Klinische Pädiatrie, 1987-03, Vol.199 (2), p.73-76 |
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| language | ger |
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| source | MEDLINE; Thieme Connect Journals |
| subjects | Adolescent Adult Blood Proteins - metabolism Child Child, Preschool Enteral Nutrition Humans Neoplasm Recurrence, Local - complications Neoplasms - complications Parenteral Nutrition Prealbumin - metabolism Protein-Energy Malnutrition - blood Protein-Energy Malnutrition - diagnosis Protein-Energy Malnutrition - therapy Retinol-Binding Proteins - metabolism Serum Albumin - metabolism Transferrin - metabolism |
| title | Protein malnutrition in pediatric patients with oncologic diseases |
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