The influence of the estrous cycle, persistent estrus, ovariectomy and estrogen replacement, on the numbers and frequency of spontaneously active neurons in slices of the rat preoptic region in vitro
Spontaneous single-unit activity was studied in the preoptic region of rat brain slices. Similar unit frequencies were recorded during the estrous cycle and for all ovariectomized (OVX) rats (median frequencies between 0.8 and 2.0 Hz). Higher frequencies were recorded in persistent estrus (PE) (medi...
Gespeichert in:
| Veröffentlicht in: | Neuroscience letters 1987-05, Vol.76 (3), p.323-328 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 328 |
|---|---|
| container_issue | 3 |
| container_start_page | 323 |
| container_title | Neuroscience letters |
| container_volume | 76 |
| creator | Sibbald, J.R. Sirett, N.E. Hubbard, J.I. |
| description | Spontaneous single-unit activity was studied in the preoptic region of rat brain slices. Similar unit frequencies were recorded during the estrous cycle and for all ovariectomized (OVX) rats (median frequencies between 0.8 and 2.0 Hz). Higher frequencies were recorded in persistent estrus (PE) (median 3.5 Hz) and in males (median 3.4 Hz), P vs estrus |
| doi_str_mv | 10.1016/0304-3940(87)90423-X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_77536365</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>030439408790423X</els_id><sourcerecordid>77536365</sourcerecordid><originalsourceid>FETCH-LOGICAL-c301t-4b82a90b71d98eea0455906ffb5e03a967e2655039b2f169f5ed0ef8765713193</originalsourceid><addsrcrecordid>eNp9kd-K1TAQxoMo63H1DRRyIaKw1aRpmuZmQRb_wYI3K-xdSNPJGmmTmqQHzhP6Wqanx3PpVSDzm--bmQ-hl5S8p4S2HwgjTcVkQ9524p0kTc2q-0doRztRV0KK-jHanZGn6FlKvwghnPLmAl0w3gnR1jv05-4nYOftuIA3gIPFuXxAyjEsCZuDGeEKzxCTSxl8PlaWdIXDXkcHJofpgLUfto4H8DjCPGoDU4EL5Y9yfpn6InEEbYTfq9dh9Upz8Fl7KF5j0THZ7QsNSww-lalwGp2B9G-qqDOeI4Q5O1N8HlyRL9DeFevn6InVY4IXp_cS_fj86e7ma3X7_cu3m4-3lWGE5qrpu1pL0gs6yA5Ak4ZzSVprew6EadkKqFvOCZN9bWkrLYeBgO1EywVlVLJL9GbTnWMoe6SsJpcMjOO2hRKCs5a1vIDNBpoYUopg1RzdpONBUaLW_NQajlrDUZ1Qx_zUfWl7ddJf-gmGc9MpsFJ_farrZPRoo_bGpTO22jPCCna9YVBusXcQVTJuTXhwsaSmhuD-P8dfoJ-7qA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>77536365</pqid></control><display><type>article</type><title>The influence of the estrous cycle, persistent estrus, ovariectomy and estrogen replacement, on the numbers and frequency of spontaneously active neurons in slices of the rat preoptic region in vitro</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Sibbald, J.R. ; Sirett, N.E. ; Hubbard, J.I.</creator><creatorcontrib>Sibbald, J.R. ; Sirett, N.E. ; Hubbard, J.I.</creatorcontrib><description>Spontaneous single-unit activity was studied in the preoptic region of rat brain slices. Similar unit frequencies were recorded during the estrous cycle and for all ovariectomized (OVX) rats (median frequencies between 0.8 and 2.0 Hz). Higher frequencies were recorded in persistent estrus (PE) (median 3.5 Hz) and in males (median 3.4 Hz), P vs estrus <0.001. The mean percentage of tracks with units was low at estrus (15%), at diestrus (18%), in OVX rats (16%) and male rats (22%), and was significantly increased in metestrus (36%) and proestrus (33%) (P vs estrus <0.01) and in OVX rats after estrogen treatment (P<0.05 to P<0.01). It is suggested that the increased number of units found in OVX rats after estrogen treatment and in PE rats are both effects of prolonged elevated levels of estrogen in the brain.</description><identifier>ISSN: 0304-3940</identifier><identifier>EISSN: 1872-7972</identifier><identifier>DOI: 10.1016/0304-3940(87)90423-X</identifier><identifier>PMID: 3587762</identifier><identifier>CODEN: NELED5</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Action Potentials ; Animals ; Applied sciences ; Brain slice ; Diestrus - physiology ; Estradiol - physiology ; Estrogen ; Estrous cycle ; Estrus - physiology ; Exact sciences and technology ; Female ; In Vitro Techniques ; Male ; Metestrus - physiology ; Neurons - physiology ; Other techniques and industries ; Ovariectomy ; Persistent estrus ; Preoptic area ; Preoptic Area - physiology ; Proestrus - physiology ; Rat ; Rats ; Rats, Inbred Strains ; Single unit</subject><ispartof>Neuroscience letters, 1987-05, Vol.76 (3), p.323-328</ispartof><rights>1987</rights><rights>1988 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c301t-4b82a90b71d98eea0455906ffb5e03a967e2655039b2f169f5ed0ef8765713193</citedby><cites>FETCH-LOGICAL-c301t-4b82a90b71d98eea0455906ffb5e03a967e2655039b2f169f5ed0ef8765713193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0304-3940(87)90423-X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7753303$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3587762$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sibbald, J.R.</creatorcontrib><creatorcontrib>Sirett, N.E.</creatorcontrib><creatorcontrib>Hubbard, J.I.</creatorcontrib><title>The influence of the estrous cycle, persistent estrus, ovariectomy and estrogen replacement, on the numbers and frequency of spontaneously active neurons in slices of the rat preoptic region in vitro</title><title>Neuroscience letters</title><addtitle>Neurosci Lett</addtitle><description>Spontaneous single-unit activity was studied in the preoptic region of rat brain slices. Similar unit frequencies were recorded during the estrous cycle and for all ovariectomized (OVX) rats (median frequencies between 0.8 and 2.0 Hz). Higher frequencies were recorded in persistent estrus (PE) (median 3.5 Hz) and in males (median 3.4 Hz), P vs estrus <0.001. The mean percentage of tracks with units was low at estrus (15%), at diestrus (18%), in OVX rats (16%) and male rats (22%), and was significantly increased in metestrus (36%) and proestrus (33%) (P vs estrus <0.01) and in OVX rats after estrogen treatment (P<0.05 to P<0.01). It is suggested that the increased number of units found in OVX rats after estrogen treatment and in PE rats are both effects of prolonged elevated levels of estrogen in the brain.</description><subject>Action Potentials</subject><subject>Animals</subject><subject>Applied sciences</subject><subject>Brain slice</subject><subject>Diestrus - physiology</subject><subject>Estradiol - physiology</subject><subject>Estrogen</subject><subject>Estrous cycle</subject><subject>Estrus - physiology</subject><subject>Exact sciences and technology</subject><subject>Female</subject><subject>In Vitro Techniques</subject><subject>Male</subject><subject>Metestrus - physiology</subject><subject>Neurons - physiology</subject><subject>Other techniques and industries</subject><subject>Ovariectomy</subject><subject>Persistent estrus</subject><subject>Preoptic area</subject><subject>Preoptic Area - physiology</subject><subject>Proestrus - physiology</subject><subject>Rat</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Single unit</subject><issn>0304-3940</issn><issn>1872-7972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kd-K1TAQxoMo63H1DRRyIaKw1aRpmuZmQRb_wYI3K-xdSNPJGmmTmqQHzhP6Wqanx3PpVSDzm--bmQ-hl5S8p4S2HwgjTcVkQ9524p0kTc2q-0doRztRV0KK-jHanZGn6FlKvwghnPLmAl0w3gnR1jv05-4nYOftuIA3gIPFuXxAyjEsCZuDGeEKzxCTSxl8PlaWdIXDXkcHJofpgLUfto4H8DjCPGoDU4EL5Y9yfpn6InEEbYTfq9dh9Upz8Fl7KF5j0THZ7QsNSww-lalwGp2B9G-qqDOeI4Q5O1N8HlyRL9DeFevn6InVY4IXp_cS_fj86e7ma3X7_cu3m4-3lWGE5qrpu1pL0gs6yA5Ak4ZzSVprew6EadkKqFvOCZN9bWkrLYeBgO1EywVlVLJL9GbTnWMoe6SsJpcMjOO2hRKCs5a1vIDNBpoYUopg1RzdpONBUaLW_NQajlrDUZ1Qx_zUfWl7ddJf-gmGc9MpsFJ_farrZPRoo_bGpTO22jPCCna9YVBusXcQVTJuTXhwsaSmhuD-P8dfoJ-7qA</recordid><startdate>19870519</startdate><enddate>19870519</enddate><creator>Sibbald, J.R.</creator><creator>Sirett, N.E.</creator><creator>Hubbard, J.I.</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19870519</creationdate><title>The influence of the estrous cycle, persistent estrus, ovariectomy and estrogen replacement, on the numbers and frequency of spontaneously active neurons in slices of the rat preoptic region in vitro</title><author>Sibbald, J.R. ; Sirett, N.E. ; Hubbard, J.I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c301t-4b82a90b71d98eea0455906ffb5e03a967e2655039b2f169f5ed0ef8765713193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Action Potentials</topic><topic>Animals</topic><topic>Applied sciences</topic><topic>Brain slice</topic><topic>Diestrus - physiology</topic><topic>Estradiol - physiology</topic><topic>Estrogen</topic><topic>Estrous cycle</topic><topic>Estrus - physiology</topic><topic>Exact sciences and technology</topic><topic>Female</topic><topic>In Vitro Techniques</topic><topic>Male</topic><topic>Metestrus - physiology</topic><topic>Neurons - physiology</topic><topic>Other techniques and industries</topic><topic>Ovariectomy</topic><topic>Persistent estrus</topic><topic>Preoptic area</topic><topic>Preoptic Area - physiology</topic><topic>Proestrus - physiology</topic><topic>Rat</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Single unit</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sibbald, J.R.</creatorcontrib><creatorcontrib>Sirett, N.E.</creatorcontrib><creatorcontrib>Hubbard, J.I.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sibbald, J.R.</au><au>Sirett, N.E.</au><au>Hubbard, J.I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The influence of the estrous cycle, persistent estrus, ovariectomy and estrogen replacement, on the numbers and frequency of spontaneously active neurons in slices of the rat preoptic region in vitro</atitle><jtitle>Neuroscience letters</jtitle><addtitle>Neurosci Lett</addtitle><date>1987-05-19</date><risdate>1987</risdate><volume>76</volume><issue>3</issue><spage>323</spage><epage>328</epage><pages>323-328</pages><issn>0304-3940</issn><eissn>1872-7972</eissn><coden>NELED5</coden><abstract>Spontaneous single-unit activity was studied in the preoptic region of rat brain slices. Similar unit frequencies were recorded during the estrous cycle and for all ovariectomized (OVX) rats (median frequencies between 0.8 and 2.0 Hz). Higher frequencies were recorded in persistent estrus (PE) (median 3.5 Hz) and in males (median 3.4 Hz), P vs estrus <0.001. The mean percentage of tracks with units was low at estrus (15%), at diestrus (18%), in OVX rats (16%) and male rats (22%), and was significantly increased in metestrus (36%) and proestrus (33%) (P vs estrus <0.01) and in OVX rats after estrogen treatment (P<0.05 to P<0.01). It is suggested that the increased number of units found in OVX rats after estrogen treatment and in PE rats are both effects of prolonged elevated levels of estrogen in the brain.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>3587762</pmid><doi>10.1016/0304-3940(87)90423-X</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0304-3940 |
| ispartof | Neuroscience letters, 1987-05, Vol.76 (3), p.323-328 |
| issn | 0304-3940 1872-7972 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77536365 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Action Potentials Animals Applied sciences Brain slice Diestrus - physiology Estradiol - physiology Estrogen Estrous cycle Estrus - physiology Exact sciences and technology Female In Vitro Techniques Male Metestrus - physiology Neurons - physiology Other techniques and industries Ovariectomy Persistent estrus Preoptic area Preoptic Area - physiology Proestrus - physiology Rat Rats Rats, Inbred Strains Single unit |
| title | The influence of the estrous cycle, persistent estrus, ovariectomy and estrogen replacement, on the numbers and frequency of spontaneously active neurons in slices of the rat preoptic region in vitro |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T21%3A38%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20influence%20of%20the%20estrous%20cycle,%20persistent%20estrus,%20ovariectomy%20and%20estrogen%20replacement,%20on%20the%20numbers%20and%20frequency%20of%20spontaneously%20active%20neurons%20in%20slices%20of%20the%20rat%20preoptic%20region%20in%20vitro&rft.jtitle=Neuroscience%20letters&rft.au=Sibbald,%20J.R.&rft.date=1987-05-19&rft.volume=76&rft.issue=3&rft.spage=323&rft.epage=328&rft.pages=323-328&rft.issn=0304-3940&rft.eissn=1872-7972&rft.coden=NELED5&rft_id=info:doi/10.1016/0304-3940(87)90423-X&rft_dat=%3Cproquest_cross%3E77536365%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=77536365&rft_id=info:pmid/3587762&rft_els_id=030439408790423X&rfr_iscdi=true |