N-Terminus and Lysine Side Chain pKa Values of Melittin in Aqueous Solutions and Micellar Dispersions Measured by 15N NMR

Melittin (MLT) is a 26-amino acid cytolytic peptide from the Apis mellifera honey bee. It is known to exist as an alpha-helical tetramer, as an alpha-helical monomer, or as a monomeric random coil depending on solvent conditions. The charge state of MLT is believed to be a major factor in determinin...

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Veröffentlicht in:	Biochemistry (Easton) 1995-10, Vol.34 (40), p.13196-13202
Hauptverfasser:	Zhu, Lingyang, Kemple, Marvin D, Yuan, Peng, Prendergast, Franklyn G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Lysine - chemistry Macromolecular Substances Magnetic Resonance Spectroscopy Melitten - chemistry Micelles Molecular Sequence Data Protein Binding Solutions Water
Online-Zugang:	Volltext
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