The proliferative response of mouse lymphoid tissues during infections with Babesia microti or Babesia rodhaini
Inchley C. J., Grieve E. M. and Preston P. M. 1987. The proliferative response of mouse lymphoid tissues during infections with Babesia microti or Babesia rodhaini. International Journal for Parasitology 17: 945–950. Proliferative responses induced by the lethal protozoan parasite, Babesia rodhaini,...
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| creator | Inchley, C.J. Grieve, Elinor M. Preston, Patricia M. |
| description | Inchley C. J.,
Grieve E. M. and
Preston P. M. 1987. The proliferative response of mouse lymphoid tissues during infections with
Babesia microti or
Babesia rodhaini.
International Journal for Parasitology
17: 945–950. Proliferative responses induced by the lethal protozoan parasite,
Babesia rodhaini, or the non-lethal species,
B. microti were measured in the lymphoid tissues of infected mice. Both stimulated equally rapid DNA synthesis in the spleen, but spleen enlargement during the first week was more pronounced after infection with
B. rodhaini, suggesting an earlier influx of cirulating cells than during
B. microti infections. Termination of
B. rodhaini infections by chemotherapy revealed that the recruitment of cells, but not the proliferative response, was dependent on the presence of live parasites. The spleen enlargement typical of
B. microti-infected mice developed during the second week, but up to half of this response could be attributed to compensatory erythropoiesis.
Babesia microti, but not
B. rodhaini, induced a proliferative response in peripheral lymph nodes, and transiently depressed cell division in the thymus. |
| doi_str_mv | 10.1016/0020-7519(87)90013-0 |
| format | Article |
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Grieve E. M. and
Preston P. M. 1987. The proliferative response of mouse lymphoid tissues during infections with
Babesia microti or
Babesia rodhaini.
International Journal for Parasitology
17: 945–950. Proliferative responses induced by the lethal protozoan parasite,
Babesia rodhaini, or the non-lethal species,
B. microti were measured in the lymphoid tissues of infected mice. Both stimulated equally rapid DNA synthesis in the spleen, but spleen enlargement during the first week was more pronounced after infection with
B. rodhaini, suggesting an earlier influx of cirulating cells than during
B. microti infections. Termination of
B. rodhaini infections by chemotherapy revealed that the recruitment of cells, but not the proliferative response, was dependent on the presence of live parasites. The spleen enlargement typical of
B. microti-infected mice developed during the second week, but up to half of this response could be attributed to compensatory erythropoiesis.
Babesia microti, but not
B. rodhaini, induced a proliferative response in peripheral lymph nodes, and transiently depressed cell division in the thymus.</description><identifier>ISSN: 0020-7519</identifier><identifier>EISSN: 1879-0135</identifier><identifier>DOI: 10.1016/0020-7519(87)90013-0</identifier><identifier>PMID: 3583545</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Babesia - immunology ; Babesia microti ; Babesia rodhaini ; Babesiosis - immunology ; Babesiosis - pathology ; cell division ; cell proliferation ; Female ; Immunity, Cellular ; lymphatic system ; Lymphoid Tissue - immunology ; Lymphoid Tissue - pathology ; lymphoid tissues ; Mice ; mouse ; Organ Size ; Spleen - immunology ; Spleen - pathology ; splenomegaly</subject><ispartof>International journal for parasitology, 1987-04, Vol.17 (4), p.945-950</ispartof><rights>1987</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c412t-e3241cc46fa70d0c784233864f7b55daf270debfb01891fb630a8781314f982f3</citedby><cites>FETCH-LOGICAL-c412t-e3241cc46fa70d0c784233864f7b55daf270debfb01891fb630a8781314f982f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0020751987900130$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3583545$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Inchley, C.J.</creatorcontrib><creatorcontrib>Grieve, Elinor M.</creatorcontrib><creatorcontrib>Preston, Patricia M.</creatorcontrib><title>The proliferative response of mouse lymphoid tissues during infections with Babesia microti or Babesia rodhaini</title><title>International journal for parasitology</title><addtitle>Int J Parasitol</addtitle><description>Inchley C. J.,
Grieve E. M. and
Preston P. M. 1987. The proliferative response of mouse lymphoid tissues during infections with
Babesia microti or
Babesia rodhaini.
International Journal for Parasitology
17: 945–950. Proliferative responses induced by the lethal protozoan parasite,
Babesia rodhaini, or the non-lethal species,
B. microti were measured in the lymphoid tissues of infected mice. Both stimulated equally rapid DNA synthesis in the spleen, but spleen enlargement during the first week was more pronounced after infection with
B. rodhaini, suggesting an earlier influx of cirulating cells than during
B. microti infections. Termination of
B. rodhaini infections by chemotherapy revealed that the recruitment of cells, but not the proliferative response, was dependent on the presence of live parasites. The spleen enlargement typical of
B. microti-infected mice developed during the second week, but up to half of this response could be attributed to compensatory erythropoiesis.
Babesia microti, but not
B. rodhaini, induced a proliferative response in peripheral lymph nodes, and transiently depressed cell division in the thymus.</description><subject>Animals</subject><subject>Babesia - immunology</subject><subject>Babesia microti</subject><subject>Babesia rodhaini</subject><subject>Babesiosis - immunology</subject><subject>Babesiosis - pathology</subject><subject>cell division</subject><subject>cell proliferation</subject><subject>Female</subject><subject>Immunity, Cellular</subject><subject>lymphatic system</subject><subject>Lymphoid Tissue - immunology</subject><subject>Lymphoid Tissue - pathology</subject><subject>lymphoid tissues</subject><subject>Mice</subject><subject>mouse</subject><subject>Organ Size</subject><subject>Spleen - immunology</subject><subject>Spleen - pathology</subject><subject>splenomegaly</subject><issn>0020-7519</issn><issn>1879-0135</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcFu1DAQhi0EKtvCG4DwCcEhxRPbsXNBgqoUpEo90J4tJxl3ByXxYmdb9e3xsqs9wsnjmW9G8__D2BsQ5yCg-SRELSqjof1gzcdWCJCVeMZWYE1blY9-zlZH5CU7zflXYbRU6oSdSG2lVnrF4u0a-SbFkQImv9AD8oR5E-eMPAY-xW0Jxqdps4408IVy3mLmwzbRfM9pDtgvVGD-SMuaf_UdZvJ8oj7FhXhMx1SKw9rTTK_Yi-DHjK8P7xm7-3Z5e_G9ur65-nHx5brqFdRLhbJW0PeqCd6IQfTGqlpK26hgOq0HH-qSxi50AmwLoWuk8NZYkKBCa-sgz9j7_dyi7XdZeXET5R7H0c9YNDljtATRwn9BUEa20LQFVHuwaMs5YXCbRJNPTw6E2x3E7dx2O7edNe7vQZwobW8P87fdhMOx6XCBUn-3rwcfnb9PlN3dz7r0CiiSjd5N-LwnsPj1QJhc7gnnHgdKxX43RPr3Cn8AqxOkKw</recordid><startdate>19870401</startdate><enddate>19870401</enddate><creator>Inchley, C.J.</creator><creator>Grieve, Elinor M.</creator><creator>Preston, Patricia M.</creator><general>Elsevier Ltd</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>19870401</creationdate><title>The proliferative response of mouse lymphoid tissues during infections with Babesia microti or Babesia rodhaini</title><author>Inchley, C.J. ; Grieve, Elinor M. ; Preston, Patricia M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c412t-e3241cc46fa70d0c784233864f7b55daf270debfb01891fb630a8781314f982f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Animals</topic><topic>Babesia - immunology</topic><topic>Babesia microti</topic><topic>Babesia rodhaini</topic><topic>Babesiosis - immunology</topic><topic>Babesiosis - pathology</topic><topic>cell division</topic><topic>cell proliferation</topic><topic>Female</topic><topic>Immunity, Cellular</topic><topic>lymphatic system</topic><topic>Lymphoid Tissue - immunology</topic><topic>Lymphoid Tissue - pathology</topic><topic>lymphoid tissues</topic><topic>Mice</topic><topic>mouse</topic><topic>Organ Size</topic><topic>Spleen - immunology</topic><topic>Spleen - pathology</topic><topic>splenomegaly</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Inchley, C.J.</creatorcontrib><creatorcontrib>Grieve, Elinor M.</creatorcontrib><creatorcontrib>Preston, Patricia M.</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>International journal for parasitology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Inchley, C.J.</au><au>Grieve, Elinor M.</au><au>Preston, Patricia M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The proliferative response of mouse lymphoid tissues during infections with Babesia microti or Babesia rodhaini</atitle><jtitle>International journal for parasitology</jtitle><addtitle>Int J Parasitol</addtitle><date>1987-04-01</date><risdate>1987</risdate><volume>17</volume><issue>4</issue><spage>945</spage><epage>950</epage><pages>945-950</pages><issn>0020-7519</issn><eissn>1879-0135</eissn><abstract>Inchley C. J.,
Grieve E. M. and
Preston P. M. 1987. The proliferative response of mouse lymphoid tissues during infections with
Babesia microti or
Babesia rodhaini.
International Journal for Parasitology
17: 945–950. Proliferative responses induced by the lethal protozoan parasite,
Babesia rodhaini, or the non-lethal species,
B. microti were measured in the lymphoid tissues of infected mice. Both stimulated equally rapid DNA synthesis in the spleen, but spleen enlargement during the first week was more pronounced after infection with
B. rodhaini, suggesting an earlier influx of cirulating cells than during
B. microti infections. Termination of
B. rodhaini infections by chemotherapy revealed that the recruitment of cells, but not the proliferative response, was dependent on the presence of live parasites. The spleen enlargement typical of
B. microti-infected mice developed during the second week, but up to half of this response could be attributed to compensatory erythropoiesis.
Babesia microti, but not
B. rodhaini, induced a proliferative response in peripheral lymph nodes, and transiently depressed cell division in the thymus.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>3583545</pmid><doi>10.1016/0020-7519(87)90013-0</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | International journal for parasitology, 1987-04, Vol.17 (4), p.945-950 |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals Babesia - immunology Babesia microti Babesia rodhaini Babesiosis - immunology Babesiosis - pathology cell division cell proliferation Female Immunity, Cellular lymphatic system Lymphoid Tissue - immunology Lymphoid Tissue - pathology lymphoid tissues Mice mouse Organ Size Spleen - immunology Spleen - pathology splenomegaly |
| title | The proliferative response of mouse lymphoid tissues during infections with Babesia microti or Babesia rodhaini |
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