Role of the thymus and T-cells in slow growth of B16 melanoma in old mice

Clinical observations suggest that tumors grow more slowly in aged subjects. To investigate the influence of age on tumor growth, we injected the same number of cultured B16 melanoma cells into C57BL/6 mice of various ages. B16 melanoma cells, inoculated s.c., grew more slowly in old (18-20-month-ol...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1987-06, Vol.47 (12), p.3097-3100
Hauptverfasser:	TSUDA, T, YOUNG TAI KIM, SISKIND, G. W, DEBLASIO, A, SCHWAB, R, ERSHLER, W, WEKSLER, M. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animal tumors. Experimental tumors Animals Biological and medical sciences Cell Division Cell Line Concanavalin A - pharmacology Experimental skin tumors Medical sciences Melanoma - pathology Mice Mice, Inbred C57BL Phytohemagglutinins - pharmacology Spleen - cytology T-Lymphocytes - physiology Thymus Gland - physiology Tumors
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