Novel 4'-substituted and 4',4-disubstituted 3α-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors

A series of 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs were prepared as novel probes for the dopamine transporter. These compounds were evaluated in radiolabeled binding assays for the dopamine, norepinephrine, and serotonin transporters. All of th...

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Veröffentlicht in:Journal of medicinal chemistry 1995-09, Vol.38 (20), p.3933-3940
Hauptverfasser: NEWMAN, A. H, KLINE, R. H, ALLEN, A. C, IZENWASSER, S, GEORGE, C, KATZ, J. L
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Sprache:eng
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