Small-conductance chloride channels in human peripheral T lymphocytes

During whole-cell patch-clamp recording from normal (nontransformed) human T lymphocytes a chloride current spontaneously activated in > 98% of cells (n > 200) in the absence of applied osmotic or pressure gradients. However, some volume sensitivity was observed, as negative pressure pulses re...

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Veröffentlicht in:	The Journal of membrane biology 1995-06, Vol.145 (3), p.217-232
Hauptverfasser:	Schumacher, P A, Sakellaropoulos, G, Phipps, D J, Schlichter, L C
Format:	Artikel
Sprache:	eng
Schlagworte:	Biophysical Phenomena Biophysics Cell Membrane - metabolism Chloride Channels - antagonists & inhibitors Chloride Channels - drug effects Chloride Channels - metabolism Electric Conductivity Glycolates - pharmacology Humans In Vitro Techniques Ion Transport Kinetics Membrane Potentials Nitrobenzoates - pharmacology T-Lymphocytes - metabolism
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