Antagonistic activity of 24-oxa-analogs of vitamin D

24-Oxa-vitamin D 3 (24-oxa-D 3) and 24-oxa-1α-hydroxyvitamin D 3 were designed as possible inhibitors of the vitamin D metabolic activation pathway. Their affinity for the vitamin D receptor (from pig intestine) and human vitamin binding protein were reduced, and their potency to induce cell differe...

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Veröffentlicht in:	Steroids 1995-06, Vol.60 (6), p.484-490
Hauptverfasser:	Allewaert, Katrien, Sarandeses, Luis A., Mourino, Antonio, Convents, Renilde, Tan, Biauw-Keng, Zhao, Jie, Bouillon, Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	agonist Animals antagonist Biological and medical sciences calcemic effect Calcitriol - pharmacology Calcium - blood Cell Differentiation - drug effects Chickens cholecalciferol Cholecalciferol - analogs & derivatives Cholecalciferol - metabolism Cholecalciferol - pharmacology differentiation Hormones. Endocrine system Humans Leukemia, Promyelocytic, Acute Medical sciences Osteosarcoma Pharmacology. Drug treatments receptor Receptors, Calcitriol - metabolism Swine Tumor Cells, Cultured Vitamin D - antagonists & inhibitors Vitamin D-Binding Protein - metabolism
Online-Zugang:	Volltext
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