Burn Injury Induces a Biphasic Immunoglobulin M Response to Bacterial Antigen

We studied 75 BALB/c mice to examine the role of impaired imunnoglobulin M (IgM) synthesis in the increased risk of bacterial infection after burn injury by investigating the kinetics of IgM synthesis to peptidoglycan polysaccharide (PGPS), a ubiquitous bacterial antigen. Splenocytes were isolated 1...

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Veröffentlicht in:	The Journal of Trauma: Injury, Infection, and Critical Care Infection, and Critical Care, 1995-08, Vol.39 (2), p.279-284
Hauptverfasser:	Yamamoto, Hiromasa, Hayes, Yumiko O., deSerres, Suzan, Chang, Jerjang, Tabata, Takashi, Meyer, Anthony A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Infections - immunology Burns - immunology Burns - metabolism Cells, Cultured Enzyme-Linked Immunosorbent Assay Immunoglobulin M - biosynthesis Lipopolysaccharides - immunology Male Mice Mice, Inbred BALB C Peptidoglycan - immunology Spleen - immunology Spleen - metabolism
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