The alpha 1d-adrenoceptor subtype is involved in the noradrenaline-induced contractions of rat aorta

The pA2 value of several alpha 1-adrenoceptor antagonists on noradrenaline-induced contractions of rat aorta, and their affinity for the cloned alpha 1a-, alpha 1b- and alpha 1d-adrenoceptor subtypes were evaluated. Selective or moderately selective alpha 1d-, partially selective alpha 1b-, selectiv...

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Veröffentlicht in:	Life sciences (1973) 1995, Vol.57 (13), p.PL159-PL163
Hauptverfasser:	Testa, R, Destefani, C, Guarneri, L, Poggesi, E, Simonazzi, I, Taddei, C, Leonardi, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Antagonists - pharmacology Animals Aorta - physiology Ligands Male Muscle Contraction - drug effects Muscle Contraction - physiology Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - physiology Norepinephrine - pharmacology Rats Rats, Sprague-Dawley Receptors, Adrenergic, alpha-1 - classification Receptors, Adrenergic, alpha-1 - physiology
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