Single-Channel and Genetic Analyses Reveal Two Distinct A-Type Potassium Channels in Drosophila

Whole-cell and single-channel voltage-clamp techniques were used to identify and characterize the channels underlying the fast transient potassium current (A current) in cultured myotubes and neurons of Drosophila. The myotube (A$_{1}$) and neuronal (A$_{2}$) channels are distinct, differing in cond...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1987-05, Vol.236 (4805), p.1094-1098
Hauptverfasser:	Solc, Charles K., Zagotta, William N., Aldrich, Richard W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Atoms & subatomic particles Behavior Biological and medical sciences Classical genetics, quantitative genetics, hybrids Drosophila Drosophila - genetics Drosophila - metabolism Drosophila melanogaster Drosophilidae Electric potential Electrophysiology Fundamental and applied biological sciences. Psychology Genetic mutation Genetics Genetics of eukaryotes. Biological and molecular evolution Invertebrata Ion channels Ion Channels - metabolism ions Kinetics Larvae Muscle fibers Muscles - metabolism Mutation Neural circuitry Neurons Neurons - metabolism Neuroscience Physics Potassium Potassium (Nutrient) Potassium - metabolism Potassium in the body
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