Kinetics of smooth and skeletal muscle activation by laser pulse photolysis of caged inositol 1,4,5-trisphosphate

Inositol 1,4,5-trisphosphate (InsP3) can stimulate skinned smooth and skeletal muscle to contract by initiating Ca2+ release from the sarcoplasmic reticulum. Whether this process is an integral component of the in vivo muscle activation mechanism was tested by releasing InsP3 rapidly within skinned...

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Veröffentlicht in:Nature (London) 1987-05, Vol.327 (6119), p.249-252
Hauptverfasser: Walker, J. W, Somlyo, A. V, Goldman, Y. E, Somlyo, A. P, Trentham, D. R
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Sprache:eng
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