Regulation of cytolytic T-lymphocyte generation by B-cell stimulatory factor

The growth and differentiation of cytolytic T lymphocytes (CTL) is regulated by soluble growth hormones, of which interleukin-2 (IL-2) is considered to be of prime importance. Here we report that the lymphokine B-cell stimulatory factor (BSF-1 or interleukin-4) also has profound effects on the gener...

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Veröffentlicht in:	Nature (London) 1987-04, Vol.326 (6115), p.795-798
Hauptverfasser:	Widmer, Michael B, Grabstein, Kenneth H
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals Biological and medical sciences Cell Differentiation - drug effects Cell Division - drug effects Cellular biology Fundamental and applied biological sciences. Psychology Fundamental immunology Growth Substances - pharmacology Hormones Immunobiology Interleukin-2 - pharmacology Interleukin-4 Lymphocytes Lymphokines - pharmacology Lymphokines, interleukins ( function, expression) Mice Mice, Inbred C57BL Mice, Inbred DBA Recombinant Proteins - pharmacology Regulatory factors and their cellular receptors T-Lymphocytes, Cytotoxic - cytology T-Lymphocytes, Cytotoxic - drug effects
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