Inhibition of Proteoglycan Synthesis Influences Regeneration of Goldfish Retinal Axons on Polylysine and Laminin

Previous studies have shown that goldfish retinal axons regenerating in vivo transport increased radioactivity in the glycosaminoglycan (GAG) components of proteoglycans (PGs). During this enhanced transport, the ratio of chondroitin sulfate (CS) to heparan sulfate (HS) was 60/40. In the present inv...

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Veröffentlicht in:	Experimental neurology 1995-07, Vol.134 (1), p.126-134
Hauptverfasser:	Challacombe, Jean F., Elam, John S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - drug effects Axons - physiology Biological and medical sciences Chondroitin Sulfates - metabolism Culture Media Development. Senescence. Regeneration. Transplantation Fundamental and applied biological sciences. Psychology Goldfish Heparitin Sulfate - metabolism Hymecromone - analogs & derivatives Hymecromone - pharmacology Laminin Nerve Regeneration - physiology Polylysine Proteoglycans - antagonists & inhibitors Proteoglycans - physiology Retina - physiology Retina - ultrastructure Sulfates - metabolism Vertebrates: nervous system and sense organs
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