φX174 lysis requires slyD, a host gene which is related to the FKBP family of peptidyl-prolyl cis-trans isomerases

Recessive mutations in the slyD (sensitivity to lysis) gene were isolated by selecting for survival after induction of the cloned lysis gene E of bacteriophage φX174 [1]. The slyD − mutation, transduced into the normal φX174 host, Escherichia coli C, confers an absolute block on the plaque-forming a...

Ausführliche Beschreibung