Mesenchymal chondrosarcoma A cytogenetic, immunohistochemical and ultrastructural study

A case of mesenchymal chondrosarcoma was studied. The tumor was near-tetraploid and the clonal structural chromosomal abnormalities included add(7)(p13), add(22)(q13), markers, and double minutes. The ultrastructural and immunohistochemical findings were consistent with the diagnosis. Strong immunor...

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Veröffentlicht in:Cancer genetics and cytogenetics 1995-08, Vol.83 (1), p.56-60
Hauptverfasser: Dobin, Sheila M., Donner, Ludvik R., Speights, V.O.
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Donner, Ludvik R.
Speights, V.O.
description A case of mesenchymal chondrosarcoma was studied. The tumor was near-tetraploid and the clonal structural chromosomal abnormalities included add(7)(p13), add(22)(q13), markers, and double minutes. The ultrastructural and immunohistochemical findings were consistent with the diagnosis. Strong immunoreactivity for desmin was an unusual, not previously reported, feature of the neoplasm.
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subjects Biological and medical sciences
Bone Neoplasms - genetics
Bone Neoplasms - pathology
Bone Neoplasms - ultrastructure
Chondrosarcoma, Mesenchymal - genetics
Chondrosarcoma, Mesenchymal - pathology
Chondrosarcoma, Mesenchymal - ultrastructure
Chromosomes, Human, Pair 22
Chromosomes, Human, Pair 7
Diseases of the osteoarticular system
Humans
Immunohistochemistry
Infant
Karyotyping
Male
Medical sciences
Ploidies
Tumors of striated muscle and skeleton
title Mesenchymal chondrosarcoma A cytogenetic, immunohistochemical and ultrastructural study
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