Mesenchymal chondrosarcoma A cytogenetic, immunohistochemical and ultrastructural study
A case of mesenchymal chondrosarcoma was studied. The tumor was near-tetraploid and the clonal structural chromosomal abnormalities included add(7)(p13), add(22)(q13), markers, and double minutes. The ultrastructural and immunohistochemical findings were consistent with the diagnosis. Strong immunor...
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Veröffentlicht in: | Cancer genetics and cytogenetics 1995-08, Vol.83 (1), p.56-60 |
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description | A case of mesenchymal chondrosarcoma was studied. The tumor was near-tetraploid and the clonal structural chromosomal abnormalities included add(7)(p13), add(22)(q13), markers, and double minutes. The ultrastructural and immunohistochemical findings were consistent with the diagnosis. Strong immunoreactivity for desmin was an unusual, not previously reported, feature of the neoplasm. |
doi_str_mv | 10.1016/0165-4608(95)00031-3 |
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The tumor was near-tetraploid and the clonal structural chromosomal abnormalities included add(7)(p13), add(22)(q13), markers, and double minutes. The ultrastructural and immunohistochemical findings were consistent with the diagnosis. Strong immunoreactivity for desmin was an unusual, not previously reported, feature of the neoplasm.</description><identifier>ISSN: 0165-4608</identifier><identifier>EISSN: 1873-4456</identifier><identifier>DOI: 10.1016/0165-4608(95)00031-3</identifier><identifier>PMID: 7656206</identifier><identifier>CODEN: CGCYDF</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Biological and medical sciences ; Bone Neoplasms - genetics ; Bone Neoplasms - pathology ; Bone Neoplasms - ultrastructure ; Chondrosarcoma, Mesenchymal - genetics ; Chondrosarcoma, Mesenchymal - pathology ; Chondrosarcoma, Mesenchymal - ultrastructure ; Chromosomes, Human, Pair 22 ; Chromosomes, Human, Pair 7 ; Diseases of the osteoarticular system ; Humans ; Immunohistochemistry ; Infant ; Karyotyping ; Male ; Medical sciences ; Ploidies ; Tumors of striated muscle and skeleton</subject><ispartof>Cancer genetics and cytogenetics, 1995-08, Vol.83 (1), p.56-60</ispartof><rights>1995</rights><rights>1995 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-5640101bccb7f5e78634921b8b601153a2ef926c3775d5f5ddb48e8fd4e9ce8f3</citedby><cites>FETCH-LOGICAL-c386t-5640101bccb7f5e78634921b8b601153a2ef926c3775d5f5ddb48e8fd4e9ce8f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0165-4608(95)00031-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3649550$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7656206$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dobin, Sheila M.</creatorcontrib><creatorcontrib>Donner, Ludvik R.</creatorcontrib><creatorcontrib>Speights, V.O.</creatorcontrib><title>Mesenchymal chondrosarcoma A cytogenetic, immunohistochemical and ultrastructural study</title><title>Cancer genetics and cytogenetics</title><addtitle>Cancer Genet Cytogenet</addtitle><description>A case of mesenchymal chondrosarcoma was studied. The tumor was near-tetraploid and the clonal structural chromosomal abnormalities included add(7)(p13), add(22)(q13), markers, and double minutes. The ultrastructural and immunohistochemical findings were consistent with the diagnosis. Strong immunoreactivity for desmin was an unusual, not previously reported, feature of the neoplasm.</description><subject>Biological and medical sciences</subject><subject>Bone Neoplasms - genetics</subject><subject>Bone Neoplasms - pathology</subject><subject>Bone Neoplasms - ultrastructure</subject><subject>Chondrosarcoma, Mesenchymal - genetics</subject><subject>Chondrosarcoma, Mesenchymal - pathology</subject><subject>Chondrosarcoma, Mesenchymal - ultrastructure</subject><subject>Chromosomes, Human, Pair 22</subject><subject>Chromosomes, Human, Pair 7</subject><subject>Diseases of the osteoarticular system</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Infant</subject><subject>Karyotyping</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Ploidies</subject><subject>Tumors of striated muscle and skeleton</subject><issn>0165-4608</issn><issn>1873-4456</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE2LFDEQhoMo6-zqP1Dog8gKtiadr85FWBa_YJe9KB5DulLtRLo7a5JemH-_GWeYo4dQkHreouoh5BWjHxhl6mN9shWK9pdGvqOUctbyJ2TDes1bIaR6SjYn5Dk5z_lPhXRn1Bk500qqjqoN-XWLGRfY7mY3NbCNi08xuwRxds1VA7sSf-OCJcD7JszzusRtyCXCFucANeEW36xTSS6XtEJZU_3LZfW7F-TZ6KaML4_1gvz88vnH9bf25u7r9-urmxZ4r0orlaD1mAFg0KNE3SsuTMeGflCUMcldh6PpFHCtpZej9H4QPfajF2igVn5B3h7m3qf4d8Vc7Bwy4DS5BeOardbCUN6ZCooDCPXAnHC09ynMLu0so3bv0-5l2b0sa6T959PyGnt9nL8OM_pT6Ciw9t8c-y5XIWNyC4R8wrgSRkpasU8HDKuLh4DJZgjVO_qQEIr1Mfx_j0fonJK2</recordid><startdate>19950801</startdate><enddate>19950801</enddate><creator>Dobin, Sheila M.</creator><creator>Donner, Ludvik R.</creator><creator>Speights, V.O.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19950801</creationdate><title>Mesenchymal chondrosarcoma A cytogenetic, immunohistochemical and ultrastructural study</title><author>Dobin, Sheila M. ; Donner, Ludvik R. ; Speights, V.O.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-5640101bccb7f5e78634921b8b601153a2ef926c3775d5f5ddb48e8fd4e9ce8f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Biological and medical sciences</topic><topic>Bone Neoplasms - genetics</topic><topic>Bone Neoplasms - pathology</topic><topic>Bone Neoplasms - ultrastructure</topic><topic>Chondrosarcoma, Mesenchymal - genetics</topic><topic>Chondrosarcoma, Mesenchymal - pathology</topic><topic>Chondrosarcoma, Mesenchymal - ultrastructure</topic><topic>Chromosomes, Human, Pair 22</topic><topic>Chromosomes, Human, Pair 7</topic><topic>Diseases of the osteoarticular system</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Infant</topic><topic>Karyotyping</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Ploidies</topic><topic>Tumors of striated muscle and skeleton</topic><toplevel>online_resources</toplevel><creatorcontrib>Dobin, Sheila M.</creatorcontrib><creatorcontrib>Donner, Ludvik R.</creatorcontrib><creatorcontrib>Speights, V.O.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer genetics and cytogenetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dobin, Sheila M.</au><au>Donner, Ludvik R.</au><au>Speights, V.O.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mesenchymal chondrosarcoma A cytogenetic, immunohistochemical and ultrastructural study</atitle><jtitle>Cancer genetics and cytogenetics</jtitle><addtitle>Cancer Genet Cytogenet</addtitle><date>1995-08-01</date><risdate>1995</risdate><volume>83</volume><issue>1</issue><spage>56</spage><epage>60</epage><pages>56-60</pages><issn>0165-4608</issn><eissn>1873-4456</eissn><coden>CGCYDF</coden><abstract>A case of mesenchymal chondrosarcoma was studied. The tumor was near-tetraploid and the clonal structural chromosomal abnormalities included add(7)(p13), add(22)(q13), markers, and double minutes. The ultrastructural and immunohistochemical findings were consistent with the diagnosis. Strong immunoreactivity for desmin was an unusual, not previously reported, feature of the neoplasm.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>7656206</pmid><doi>10.1016/0165-4608(95)00031-3</doi><tpages>5</tpages></addata></record> |
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subjects | Biological and medical sciences Bone Neoplasms - genetics Bone Neoplasms - pathology Bone Neoplasms - ultrastructure Chondrosarcoma, Mesenchymal - genetics Chondrosarcoma, Mesenchymal - pathology Chondrosarcoma, Mesenchymal - ultrastructure Chromosomes, Human, Pair 22 Chromosomes, Human, Pair 7 Diseases of the osteoarticular system Humans Immunohistochemistry Infant Karyotyping Male Medical sciences Ploidies Tumors of striated muscle and skeleton |
title | Mesenchymal chondrosarcoma A cytogenetic, immunohistochemical and ultrastructural study |
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