Comparison of Fluorine-18-Fluorodeoxyglucose and Tritiated Fluoromisonidazole Uptake during Low-Flow Ischemia

Fluorine-18-fluoromisonidazole (FMISO) is trapped in hypoxic but viable canine myocardium. Because of the potential for its use as a marker of myocardial viability, we compared FMISO activity to [18F]fluorodeoxyglucose (FDG) activity in the same myocardial samples from eight dogs subjected to 3 hr o...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 1995-09, Vol.36 (9), p.1633-1638
Hauptverfasser:	Caldwell, J.H, Revenaugh, J.R, Martin, G.V, Johnson, P.M, Rasey, J.S, Krohn, K.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Contrast media. Radiopharmaceuticals Coronary Circulation Deoxyglucose - analogs & derivatives Deoxyglucose - pharmacokinetics Dogs Fluorine Radioisotopes - pharmacokinetics Fluorodeoxyglucose F18 Heart - diagnostic imaging Medical sciences Misonidazole - analogs & derivatives Misonidazole - pharmacokinetics Myocardial Ischemia - diagnostic imaging Myocardial Ischemia - metabolism Myocardial Ischemia - physiopathology Pharmacology. Drug treatments Radionuclide Imaging Sensitivity and Specificity Tritium - pharmacokinetics
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