Increased Human Immunodeficiency Virus (HIV) Type 1 DNA Content and Quinolinic Acid Concentration in Brain Tissues from Patients with HIV Encephalopathy

Levels of human immunodeficiency virus type 1 (HIV-l) DNA and quinolinic acid were examined in areas of the central nervous system (CNS) and lymphoid organs (LN) from 5 AIDS patients with no clinically apparent CNS compromise (group I), 7 with CNS opportunistic diseases (group II), and 8 with HIV en...

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Veröffentlicht in:	The Journal of infectious diseases 1995-09, Vol.172 (3), p.638-647
Hauptverfasser:	Sei, Shizuko, Saito, Kuniaki, Stewart, Sean K., Crowley, Jeffrey S., Brouwers, Pim, Kleiner, David E., Katz, David A., Pizzo, Philip A., Heyes, Melvyn P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult AIDS AIDS dementia complex AIDS Dementia Complex - drug therapy AIDS Dementia Complex - pathology AIDS Dementia Complex - virology AIDS-Related Opportunistic Infections - pathology AIDS-Related Opportunistic Infections - virology AIDS/HIV Base Sequence Biological and medical sciences Brain Brain - virology Brain Chemistry Cells, Cultured Central nervous system Cerebellum - virology Child Child, Preschool Didanosine - therapeutic use DNA Primers DNA, Viral - analysis Genes, pol Genetic mutation HIV HIV 1 HIV-1 - genetics HIV-1 - isolation & purification human immunodeficiency virus 1 Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infant Infections Macrophages Macrophages - virology Major Articles Medical sciences Middle Aged Molecular Sequence Data Mutation Organ Specificity Polymerase chain reaction Polymerase Chain Reaction - methods Quinolinic Acid - analysis Tumor Necrosis Factor-alpha - analysis Zidovudine - therapeutic use
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