Malignant fibrous histiocytoma of the mandible: the importance of an accurate histopathological diagnosis
A case is presented of a malignant fibrous histiocytoma arising in the mandible and oral cavity of a 62-year old woman. The histopathological features were typical and the diagnosis was confirmed on immunohistochemistry. The exact nature of this usually soft tissue sarcoma is uncertain, but it is a...
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| Veröffentlicht in: | British journal of oral & maxillofacial surgery 1995-06, Vol.33 (3), p.166-168 |
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| container_end_page | 168 |
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| container_issue | 3 |
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| container_title | British journal of oral & maxillofacial surgery |
| container_volume | 33 |
| creator | Sohail, D. Kerr, R. Simpson, R.H.W. Babajews, A.V. |
| description | A case is presented of a malignant fibrous histiocytoma arising in the mandible and oral cavity of a 62-year old woman. The histopathological features were typical and the diagnosis was confirmed on immunohistochemistry. The exact nature of this usually soft tissue sarcoma is uncertain, but it is a well defined clinicopathological tumour entity which only rarely arises in the jaws. Microscopically, it may resemble other neoplasms, such as sarcomatoid squamous carcinoma, and an accurate diagnosis requires the use of immunohistochemistry or electron microscopy. Treatment is primarily surgical, but because of the difficulties at this site of complete removal with adequate margins, recurrence, metastasis and death due to disease are a likely outcome. |
| doi_str_mv | 10.1016/0266-4356(95)90290-2 |
| format | Article |
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The histopathological features were typical and the diagnosis was confirmed on immunohistochemistry. The exact nature of this usually soft tissue sarcoma is uncertain, but it is a well defined clinicopathological tumour entity which only rarely arises in the jaws. Microscopically, it may resemble other neoplasms, such as sarcomatoid squamous carcinoma, and an accurate diagnosis requires the use of immunohistochemistry or electron microscopy. 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The histopathological features were typical and the diagnosis was confirmed on immunohistochemistry. The exact nature of this usually soft tissue sarcoma is uncertain, but it is a well defined clinicopathological tumour entity which only rarely arises in the jaws. Microscopically, it may resemble other neoplasms, such as sarcomatoid squamous carcinoma, and an accurate diagnosis requires the use of immunohistochemistry or electron microscopy. Treatment is primarily surgical, but because of the difficulties at this site of complete removal with adequate margins, recurrence, metastasis and death due to disease are a likely outcome.</description><subject>Biological and medical sciences</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>Dentistry</subject><subject>Diagnosis, Differential</subject><subject>Facial bones, jaws, teeth, parodontium: diseases, semeiology</subject><subject>Female</subject><subject>Histiocytoma, Benign Fibrous - pathology</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Mandibular Neoplasms - pathology</subject><subject>Medical sciences</subject><subject>Microscopy, Electron</subject><subject>Middle Aged</subject><subject>Mouth Neoplasms - pathology</subject><subject>Non tumoral diseases</subject><subject>Otorhinolaryngology. 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Stomatology</topic><topic>Sarcoma - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sohail, D.</creatorcontrib><creatorcontrib>Kerr, R.</creatorcontrib><creatorcontrib>Simpson, R.H.W.</creatorcontrib><creatorcontrib>Babajews, A.V.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of oral & maxillofacial surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sohail, D.</au><au>Kerr, R.</au><au>Simpson, R.H.W.</au><au>Babajews, A.V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Malignant fibrous histiocytoma of the mandible: the importance of an accurate histopathological diagnosis</atitle><jtitle>British journal of oral & maxillofacial surgery</jtitle><addtitle>Br J Oral Maxillofac Surg</addtitle><date>1995-06-01</date><risdate>1995</risdate><volume>33</volume><issue>3</issue><spage>166</spage><epage>168</epage><pages>166-168</pages><issn>0266-4356</issn><eissn>1532-1940</eissn><coden>BJOSEY</coden><abstract>A case is presented of a malignant fibrous histiocytoma arising in the mandible and oral cavity of a 62-year old woman. The histopathological features were typical and the diagnosis was confirmed on immunohistochemistry. The exact nature of this usually soft tissue sarcoma is uncertain, but it is a well defined clinicopathological tumour entity which only rarely arises in the jaws. Microscopically, it may resemble other neoplasms, such as sarcomatoid squamous carcinoma, and an accurate diagnosis requires the use of immunohistochemistry or electron microscopy. Treatment is primarily surgical, but because of the difficulties at this site of complete removal with adequate margins, recurrence, metastasis and death due to disease are a likely outcome.</abstract><cop>Londonc</cop><pub>Elsevier Ltd</pub><pmid>7654661</pmid><doi>10.1016/0266-4356(95)90290-2</doi><tpages>3</tpages></addata></record> |
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| identifier | ISSN: 0266-4356 |
| ispartof | British journal of oral & maxillofacial surgery, 1995-06, Vol.33 (3), p.166-168 |
| issn | 0266-4356 1532-1940 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Biological and medical sciences Carcinoma, Squamous Cell - pathology Dentistry Diagnosis, Differential Facial bones, jaws, teeth, parodontium: diseases, semeiology Female Histiocytoma, Benign Fibrous - pathology Humans Immunohistochemistry Mandibular Neoplasms - pathology Medical sciences Microscopy, Electron Middle Aged Mouth Neoplasms - pathology Non tumoral diseases Otorhinolaryngology. Stomatology Sarcoma - pathology |
| title | Malignant fibrous histiocytoma of the mandible: the importance of an accurate histopathological diagnosis |
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