The Role of Open Lung Biopsy in Patients with the Acquired Immunodeficiency Syndrome

To assess the role of open lung biopsy in patients with the acquired immunodeficiency syndrome (AIDS), we retrospectively reviewed the cases of 42 patients with AIDS who underwent this procedure for the diagnosis of pulmonary infiltrates. Four patients had no preceding bronchoscopy because the sever...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chest 1987-05, Vol.91 (5), p.659-661
Hauptverfasser: Fitzgerald, William, Bevelaqua, Frederick A., Garay, Stuart M., Aranda, Conrado P.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 661
container_issue 5
container_start_page 659
container_title Chest
container_volume 91
creator Fitzgerald, William
Bevelaqua, Frederick A.
Garay, Stuart M.
Aranda, Conrado P.
description To assess the role of open lung biopsy in patients with the acquired immunodeficiency syndrome (AIDS), we retrospectively reviewed the cases of 42 patients with AIDS who underwent this procedure for the diagnosis of pulmonary infiltrates. Four patients had no preceding bronchoscopy because the severity of the respiratory failure or abnormalities of coagulation precluded the safe performance of this procedure. Twenty-nine cases had a preceding nondiagnostic bronchoscopic procedure, and nine others underwent open lung biopsy because of progressive deterioration despite treatment for diseases diagnosed bronchoscopically. We found that open lung biopsy was likely to be useful diagnostically when bronchoscopy could not be safely performed or when a preceding bronchoscopic procedure was not diagnostic. Open lung biopsies done on patients whose condition continued to deteriorate despite treatment for disorders established bronchoscopically were not likely to yield information therapeutically useful. In only one of nine such cases was a new treatable diagnosis obtained (Legionella). The others showed either severe pulmonary fibrosis or persistence of the initial disease process diagnosed at the time of bronchoscopy.
doi_str_mv 10.1378/chest.91.5.659
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_77478023</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0012369216587959</els_id><sourcerecordid>14952861</sourcerecordid><originalsourceid>FETCH-LOGICAL-c438t-71641e23815aaed5606fa758d2229f334bdc20806f83bab85fe86f4aba3047183</originalsourceid><addsrcrecordid>eNqFkU1v1DAQhi0EKkvhyg3JB8QtwY7jjxxLxUellYpgOVuOPW5cJfHWTqj232O6q6oXxMmy55l5R48RektJTZlUH-0Aeak7WvNa8O4Z2tCO0Yrxlj1HG0JoUzHRNS_Rq5xvSbnTTpyhM8aFkpJs0G43AP4RR8DR4-s9zHi7zjf4U4j7fMBhxt_NEmBeMr4Py4CXQl_YuzUkcPhqmtY5OvDBFsQe8M_D7FKc4DV64c2Y4c3pPEe_vnzeXX6rttdfry4vtpVtmVoqSUVLoWGKcmPAcUGEN5Ir1zRN5xlre2cbosqrYr3pFfeghG9NbxhpJVXsHH04zt2neLcWD3oK2cI4mhnimrWUrVSkYf8FadvxRglawPoI2hRzTuD1PoXJpIOmRP_1rR98645qrovv0vDuNHntJ3CP-Elwqb8_1U22ZvTJzDbkR0xRJbr2Se4Qbob7YlfnyYxjGcqOibdxTbMZn-SqYwMUv78DJJ0fPgFcabaLdjH8a-U_9OismQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>14952861</pqid></control><display><type>article</type><title>The Role of Open Lung Biopsy in Patients with the Acquired Immunodeficiency Syndrome</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Fitzgerald, William ; Bevelaqua, Frederick A. ; Garay, Stuart M. ; Aranda, Conrado P.</creator><creatorcontrib>Fitzgerald, William ; Bevelaqua, Frederick A. ; Garay, Stuart M. ; Aranda, Conrado P.</creatorcontrib><description>To assess the role of open lung biopsy in patients with the acquired immunodeficiency syndrome (AIDS), we retrospectively reviewed the cases of 42 patients with AIDS who underwent this procedure for the diagnosis of pulmonary infiltrates. Four patients had no preceding bronchoscopy because the severity of the respiratory failure or abnormalities of coagulation precluded the safe performance of this procedure. Twenty-nine cases had a preceding nondiagnostic bronchoscopic procedure, and nine others underwent open lung biopsy because of progressive deterioration despite treatment for diseases diagnosed bronchoscopically. We found that open lung biopsy was likely to be useful diagnostically when bronchoscopy could not be safely performed or when a preceding bronchoscopic procedure was not diagnostic. Open lung biopsies done on patients whose condition continued to deteriorate despite treatment for disorders established bronchoscopically were not likely to yield information therapeutically useful. In only one of nine such cases was a new treatable diagnosis obtained (Legionella). The others showed either severe pulmonary fibrosis or persistence of the initial disease process diagnosed at the time of bronchoscopy.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.91.5.659</identifier><identifier>PMID: 3568770</identifier><identifier>CODEN: CHETBF</identifier><language>eng</language><publisher>Northbrook, IL: Elsevier Inc</publisher><subject>Acquired Immunodeficiency Syndrome - diagnosis ; Acquired Immunodeficiency Syndrome - pathology ; Adult ; AIDS/HIV ; Biological and medical sciences ; Biopsy ; Bronchi ; Bronchoscopy ; Evaluation Studies as Topic ; Female ; Humans ; Immunodeficiencies ; Immunodeficiencies. Immunoglobulinopathies ; Immunopathology ; Lung - pathology ; Lung Diseases - diagnosis ; Lung Diseases - pathology ; Male ; Medical sciences ; Middle Aged ; Prognosis ; Pulmonary Alveoli ; Respiratory Tract Infections - diagnosis ; Retrospective Studies ; Therapeutic Irrigation</subject><ispartof>Chest, 1987-05, Vol.91 (5), p.659-661</ispartof><rights>1987 The American College of Chest Physicians</rights><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c438t-71641e23815aaed5606fa758d2229f334bdc20806f83bab85fe86f4aba3047183</citedby><cites>FETCH-LOGICAL-c438t-71641e23815aaed5606fa758d2229f334bdc20806f83bab85fe86f4aba3047183</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=8186941$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3568770$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fitzgerald, William</creatorcontrib><creatorcontrib>Bevelaqua, Frederick A.</creatorcontrib><creatorcontrib>Garay, Stuart M.</creatorcontrib><creatorcontrib>Aranda, Conrado P.</creatorcontrib><title>The Role of Open Lung Biopsy in Patients with the Acquired Immunodeficiency Syndrome</title><title>Chest</title><addtitle>Chest</addtitle><description>To assess the role of open lung biopsy in patients with the acquired immunodeficiency syndrome (AIDS), we retrospectively reviewed the cases of 42 patients with AIDS who underwent this procedure for the diagnosis of pulmonary infiltrates. Four patients had no preceding bronchoscopy because the severity of the respiratory failure or abnormalities of coagulation precluded the safe performance of this procedure. Twenty-nine cases had a preceding nondiagnostic bronchoscopic procedure, and nine others underwent open lung biopsy because of progressive deterioration despite treatment for diseases diagnosed bronchoscopically. We found that open lung biopsy was likely to be useful diagnostically when bronchoscopy could not be safely performed or when a preceding bronchoscopic procedure was not diagnostic. Open lung biopsies done on patients whose condition continued to deteriorate despite treatment for disorders established bronchoscopically were not likely to yield information therapeutically useful. In only one of nine such cases was a new treatable diagnosis obtained (Legionella). The others showed either severe pulmonary fibrosis or persistence of the initial disease process diagnosed at the time of bronchoscopy.</description><subject>Acquired Immunodeficiency Syndrome - diagnosis</subject><subject>Acquired Immunodeficiency Syndrome - pathology</subject><subject>Adult</subject><subject>AIDS/HIV</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Bronchi</subject><subject>Bronchoscopy</subject><subject>Evaluation Studies as Topic</subject><subject>Female</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Lung - pathology</subject><subject>Lung Diseases - diagnosis</subject><subject>Lung Diseases - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Prognosis</subject><subject>Pulmonary Alveoli</subject><subject>Respiratory Tract Infections - diagnosis</subject><subject>Retrospective Studies</subject><subject>Therapeutic Irrigation</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1v1DAQhi0EKkvhyg3JB8QtwY7jjxxLxUellYpgOVuOPW5cJfHWTqj232O6q6oXxMmy55l5R48RektJTZlUH-0Aeak7WvNa8O4Z2tCO0Yrxlj1HG0JoUzHRNS_Rq5xvSbnTTpyhM8aFkpJs0G43AP4RR8DR4-s9zHi7zjf4U4j7fMBhxt_NEmBeMr4Py4CXQl_YuzUkcPhqmtY5OvDBFsQe8M_D7FKc4DV64c2Y4c3pPEe_vnzeXX6rttdfry4vtpVtmVoqSUVLoWGKcmPAcUGEN5Ir1zRN5xlre2cbosqrYr3pFfeghG9NbxhpJVXsHH04zt2neLcWD3oK2cI4mhnimrWUrVSkYf8FadvxRglawPoI2hRzTuD1PoXJpIOmRP_1rR98645qrovv0vDuNHntJ3CP-Elwqb8_1U22ZvTJzDbkR0xRJbr2Se4Qbob7YlfnyYxjGcqOibdxTbMZn-SqYwMUv78DJJ0fPgFcabaLdjH8a-U_9OismQ</recordid><startdate>19870501</startdate><enddate>19870501</enddate><creator>Fitzgerald, William</creator><creator>Bevelaqua, Frederick A.</creator><creator>Garay, Stuart M.</creator><creator>Aranda, Conrado P.</creator><general>Elsevier Inc</general><general>American College of Chest Physicians</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19870501</creationdate><title>The Role of Open Lung Biopsy in Patients with the Acquired Immunodeficiency Syndrome</title><author>Fitzgerald, William ; Bevelaqua, Frederick A. ; Garay, Stuart M. ; Aranda, Conrado P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-71641e23815aaed5606fa758d2229f334bdc20806f83bab85fe86f4aba3047183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Acquired Immunodeficiency Syndrome - diagnosis</topic><topic>Acquired Immunodeficiency Syndrome - pathology</topic><topic>Adult</topic><topic>AIDS/HIV</topic><topic>Biological and medical sciences</topic><topic>Biopsy</topic><topic>Bronchi</topic><topic>Bronchoscopy</topic><topic>Evaluation Studies as Topic</topic><topic>Female</topic><topic>Humans</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Lung - pathology</topic><topic>Lung Diseases - diagnosis</topic><topic>Lung Diseases - pathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Prognosis</topic><topic>Pulmonary Alveoli</topic><topic>Respiratory Tract Infections - diagnosis</topic><topic>Retrospective Studies</topic><topic>Therapeutic Irrigation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fitzgerald, William</creatorcontrib><creatorcontrib>Bevelaqua, Frederick A.</creatorcontrib><creatorcontrib>Garay, Stuart M.</creatorcontrib><creatorcontrib>Aranda, Conrado P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fitzgerald, William</au><au>Bevelaqua, Frederick A.</au><au>Garay, Stuart M.</au><au>Aranda, Conrado P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Role of Open Lung Biopsy in Patients with the Acquired Immunodeficiency Syndrome</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>1987-05-01</date><risdate>1987</risdate><volume>91</volume><issue>5</issue><spage>659</spage><epage>661</epage><pages>659-661</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><coden>CHETBF</coden><abstract>To assess the role of open lung biopsy in patients with the acquired immunodeficiency syndrome (AIDS), we retrospectively reviewed the cases of 42 patients with AIDS who underwent this procedure for the diagnosis of pulmonary infiltrates. Four patients had no preceding bronchoscopy because the severity of the respiratory failure or abnormalities of coagulation precluded the safe performance of this procedure. Twenty-nine cases had a preceding nondiagnostic bronchoscopic procedure, and nine others underwent open lung biopsy because of progressive deterioration despite treatment for diseases diagnosed bronchoscopically. We found that open lung biopsy was likely to be useful diagnostically when bronchoscopy could not be safely performed or when a preceding bronchoscopic procedure was not diagnostic. Open lung biopsies done on patients whose condition continued to deteriorate despite treatment for disorders established bronchoscopically were not likely to yield information therapeutically useful. In only one of nine such cases was a new treatable diagnosis obtained (Legionella). The others showed either severe pulmonary fibrosis or persistence of the initial disease process diagnosed at the time of bronchoscopy.</abstract><cop>Northbrook, IL</cop><pub>Elsevier Inc</pub><pmid>3568770</pmid><doi>10.1378/chest.91.5.659</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0012-3692
ispartof Chest, 1987-05, Vol.91 (5), p.659-661
issn 0012-3692
1931-3543
language eng
recordid cdi_proquest_miscellaneous_77478023
source MEDLINE; Alma/SFX Local Collection
subjects Acquired Immunodeficiency Syndrome - diagnosis
Acquired Immunodeficiency Syndrome - pathology
Adult
AIDS/HIV
Biological and medical sciences
Biopsy
Bronchi
Bronchoscopy
Evaluation Studies as Topic
Female
Humans
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Lung - pathology
Lung Diseases - diagnosis
Lung Diseases - pathology
Male
Medical sciences
Middle Aged
Prognosis
Pulmonary Alveoli
Respiratory Tract Infections - diagnosis
Retrospective Studies
Therapeutic Irrigation
title The Role of Open Lung Biopsy in Patients with the Acquired Immunodeficiency Syndrome
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T13%3A48%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Role%20of%20Open%20Lung%20Biopsy%20in%20Patients%20with%20the%20Acquired%20Immunodeficiency%20Syndrome&rft.jtitle=Chest&rft.au=Fitzgerald,%20William&rft.date=1987-05-01&rft.volume=91&rft.issue=5&rft.spage=659&rft.epage=661&rft.pages=659-661&rft.issn=0012-3692&rft.eissn=1931-3543&rft.coden=CHETBF&rft_id=info:doi/10.1378/chest.91.5.659&rft_dat=%3Cproquest_cross%3E14952861%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=14952861&rft_id=info:pmid/3568770&rft_els_id=S0012369216587959&rfr_iscdi=true