Long-term changes induced by neonatal handling in the nociceptive threshold and body weight in mice

During the first 3 weeks of life, four litters of CD-1 male mice were daily handled (HA group) and four other litters were left undisturbed (UHA group). At 35 days of life, mice underwent the tail flick (TF) and hot plate (HP) tests to measure the baseline reaction to thermal nociceptive stimulation...

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