Release of substance P from the spinal dorsal horn is enhanced in polyarthritic rats

Using in situ spinal dorsal horn perfusing method in decerebrated rats, we measured the release of immunoreactive substance P (iSP) in polyarthritic rats. The spontancous release of iSP from the dorsal horn in the polyarthritic rats was significantly accelerated over that in control non-inflamed rat...

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Veröffentlicht in:	Neuroscience letters 1987-03, Vol.74 (3), p.315-319
Hauptverfasser:	Oku, Ryoya, Satoh, Masamichi, Takagi, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Arthritis - metabolism Arthritis, Experimental - metabolism Arthritis, Experimental - physiopathology Biological and medical sciences Chronic pain Decerebrate State - physiopathology Local anesthesia. Pain (treatment) Male Medical sciences Pain - physiopathology Polyarthritis Rat Rats Rats, Inbred Strains Release Spinal Cord - metabolism Spinal Cord - physiopathology Spinal dorsal horn Substance P Substance P - metabolism Synaptic Transmission
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