Independent mechanisms for long-term depression of AMPA and NMDA responses

While the mechanisms responsible for LTP and LTD of excitatory synaptic responses mediated by AMPA receptors (AMPARs) have been extensively characterized, much less is known about the regulation of NMDA receptors (NMDARs) by synaptic activity. In hippocampal CA1 cells, prolonged low frequency affere...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 1995-08, Vol.15 (2), p.417-426
Hauptverfasser:	Selig, David K., Hjelmstad, Gregory O., Herron, Caroline, Nicoll, Roger A., Malenka, Robert C.
Format:	Artikel
Sprache:	eng
Schlagworte:	6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology Animals Membrane Potentials N-Methylaspartate - pharmacology Neuronal Plasticity - drug effects Neuronal Plasticity - physiology Patch-Clamp Techniques Rats Rats, Sprague-Dawley Receptors, AMPA - drug effects Receptors, AMPA - physiology Receptors, N-Methyl-D-Aspartate - drug effects Receptors, N-Methyl-D-Aspartate - physiology Synaptic Transmission - drug effects Synaptic Transmission - physiology
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