Human monoclonal antibodies to thyroid antigens derived by hybridization of lymphocytes from a diabetic patient

Human monoclonal antibodies to human endocrine cells have been obtained following the generation of immunoglobulin-secreting interspecies lymphocyte hybridomas. Peripheral blood lymphocytes from an adult patient presenting with acute onset, Type I, diabetes mellitus were fused in vitro with mouse my...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 1987-04, Vol.36 (4), p.327-334
Hauptverfasser:	Tan, K.S., Foster, C.S., DeSilva, M., Byfield, P.G.H., Medlen, A.R., Wright, J.M., Marks, V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ANTIBODIES Antibodies, Monoclonal ANTICORPS ANTICUERPOS ANTIGENE ANTIGENOS ANTIGENS Antigens - immunology Biological and medical sciences Cell Fusion Cell Line DIABETE DIABETES Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - immunology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Epitopes - immunology Etiopathogenesis. Screening. Investigations. Target tissue resistance GLANDULA TIROIDE HIBRIDACION Humans HYBRIDATION HYBRIDIZING LINFOCITOS LYMPHOCYTE LYMPHOCYTES Lymphocytes - immunology Medical sciences Mice Receptors, Thyrotropin - immunology Thyroglobulin - immunology THYROID GLAND Thyroid Gland - immunology THYROIDE
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