Expression and regulation of vascular endothelial growth factor in osteoblasts

Bone formation is linked closely to angiogenesis. Because prostaglandin E2 (PGE2) is a potent stimulator of bone formation, its effects were evaluated on vascular endothelial growth factor, a secreted endothelial cell-specific mitogen, and a potent angiogenic protein. Prostaglandin E2 increased vasc...

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Veröffentlicht in:	Clinical orthopaedics and related research 1995-04, Vol.313 (313), p.76-80
Hauptverfasser:	HARADA, S.-I, RODAN, S. B, RODAN, G. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Line Cycloheximide - pharmacology Dexamethasone - pharmacology Dinoprostone - pharmacology Endothelial Growth Factors - biosynthesis Endothelial Growth Factors - metabolism Endothelial Growth Factors - physiology Fundamental and applied biological sciences. Psychology Gene Expression In Vitro Techniques Lymphokines - biosynthesis Lymphokines - metabolism Lymphokines - physiology Osteoblasts - metabolism Rats RNA, Messenger - genetics Skeleton and joints Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors Vertebrates: osteoarticular system, musculoskeletal system
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