Secondary malignancy of the thyroid gland and its management

Secondary cancer of the thyroid gland is widely acknowledged as infrequent but is a persistent problem requiring ongoing awareness, particularly with respect to clinical recognition and treatment. From 1978 to 1993, a 15-year period, patients demonstrating secondary involvement of the thyroid gland...

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Veröffentlicht in:Annals of surgical oncology 1995-05, Vol.2 (3), p.252-256
Hauptverfasser: Rosen, I B, Walfish, P G, Bain, J, Bedard, Y C
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container_title Annals of surgical oncology
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creator Rosen, I B
Walfish, P G
Bain, J
Bedard, Y C
description Secondary cancer of the thyroid gland is widely acknowledged as infrequent but is a persistent problem requiring ongoing awareness, particularly with respect to clinical recognition and treatment. From 1978 to 1993, a 15-year period, patients demonstrating secondary involvement of the thyroid gland as a surgical problem were collected and analyzed with regard to pathology, demography, behavior of primary and secondary disease, treatment, and patient outcome. In the 15-year span, 11 patients with secondary involvement of the thyroid gland were recognized, consisting of 3 men and 8 women with primary lesions occurring in oral cavity, esophagus, stomach, colon, pancreas, breast, skin, unknown, kidney, and lung. Needle biopsy produced a 90% malignancy rate but in only half of such cases was the diagnosis specific for secondary malignancy. Eight of 11 underwent palliative surgery, usually total thyroidectomy. No patient survived > 2 years. There was no undue surgical morbidity. One patient died of pulmonary embolus postoperatively. Secondary cancer of the thyroid is rare and can be detected by fine-needle aspiration biopsy in the face of clinical findings. Where indicated, palliative thyroidectomy can be effective, because other methods of treatment appear ineffective.
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subjects Aged
Aged, 80 and over
Biopsy, Needle
Female
Humans
Longitudinal Studies
Male
Middle Aged
Ontario - epidemiology
Survival Rate
Thyroid Neoplasms - epidemiology
Thyroid Neoplasms - mortality
Thyroid Neoplasms - pathology
Thyroid Neoplasms - radiotherapy
Thyroid Neoplasms - secondary
Thyroid Neoplasms - surgery
Thyroidectomy
Treatment Outcome
title Secondary malignancy of the thyroid gland and its management
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