Astrocytic reaction in experimental scrapie in hamsters
Severe glial reaction (gliocytosis) in hamsters infected with the 263K strain of scrapie is described. Glicytosis is an extremely rare phenomenon in scrapie-affected mice. In hamsters, however, it forms an important and stable feature of the neuropathology. Both astrocytic hyperplasia and hypertroph...
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| Veröffentlicht in: | Journal of comparative pathology 1987, Vol.97 (1), p.73-78 |
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| container_title | Journal of comparative pathology |
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| creator | Liberski, P.P. |
| description | Severe glial reaction (gliocytosis) in hamsters infected with the 263K strain of scrapie is described. Glicytosis is an extremely rare phenomenon in scrapie-affected mice. In hamsters, however, it forms an important and stable feature of the neuropathology. Both astrocytic hyperplasia and hypertrophy are described. The author discusses briefly the possible contribution of the scrapie agent and of the host used in the experiments described here to the development of glial changes. |
| doi_str_mv | 10.1016/0021-9975(87)90129-0 |
| format | Article |
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Glicytosis is an extremely rare phenomenon in scrapie-affected mice. In hamsters, however, it forms an important and stable feature of the neuropathology. Both astrocytic hyperplasia and hypertrophy are described. The author discusses briefly the possible contribution of the scrapie agent and of the host used in the experiments described here to the development of glial changes.</description><identifier>ISSN: 0021-9975</identifier><identifier>EISSN: 1532-3129</identifier><identifier>DOI: 10.1016/0021-9975(87)90129-0</identifier><identifier>PMID: 3558905</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; astrocytes ; Astrocytes - cytology ; Astrocytes - ultrastructure ; Brain - pathology ; Brain - ultrastructure ; Cricetinae ; Female ; gliocytosis ; hamsters ; hyperplasia ; hypertrophy ; Male ; nervous system diseases ; neurons ; PrPSc proteins ; scrapie ; Scrapie - pathology ; strains</subject><ispartof>Journal of comparative pathology, 1987, Vol.97 (1), p.73-78</ispartof><rights>1987</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c381t-f8a96744f869c2b76873fe24f038fa33b9fc3805e32ebc24855e7aabbc1ce8d53</citedby><cites>FETCH-LOGICAL-c381t-f8a96744f869c2b76873fe24f038fa33b9fc3805e32ebc24855e7aabbc1ce8d53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0021-9975(87)90129-0$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3558905$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liberski, P.P.</creatorcontrib><title>Astrocytic reaction in experimental scrapie in hamsters</title><title>Journal of comparative pathology</title><addtitle>J Comp Pathol</addtitle><description>Severe glial reaction (gliocytosis) in hamsters infected with the 263K strain of scrapie is described. Glicytosis is an extremely rare phenomenon in scrapie-affected mice. In hamsters, however, it forms an important and stable feature of the neuropathology. Both astrocytic hyperplasia and hypertrophy are described. The author discusses briefly the possible contribution of the scrapie agent and of the host used in the experiments described here to the development of glial changes.</description><subject>Animals</subject><subject>astrocytes</subject><subject>Astrocytes - cytology</subject><subject>Astrocytes - ultrastructure</subject><subject>Brain - pathology</subject><subject>Brain - ultrastructure</subject><subject>Cricetinae</subject><subject>Female</subject><subject>gliocytosis</subject><subject>hamsters</subject><subject>hyperplasia</subject><subject>hypertrophy</subject><subject>Male</subject><subject>nervous system diseases</subject><subject>neurons</subject><subject>PrPSc proteins</subject><subject>scrapie</subject><subject>Scrapie - pathology</subject><subject>strains</subject><issn>0021-9975</issn><issn>1532-3129</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMlOwzAQQC0EKmX5AxA9ITgEvMSxc0GqKjapEgfo2XKcMRhlw3YR_XsSUvXIaTQzbxY9hM4IviGYZLcYU5LkueBXUlznmNA8wXtoSjijCeuzfTTdIYfoKIRPjLGUnE7QhHEuc8ynSMxD9K3ZRGdmHrSJrm1mrpnBTwfe1dBEXc2C8bpzMNQ_dB0i-HCCDqyuApxu4zFaPdy_LZ6S5cvj82K-TAyTJCZW6jwTaWpllhtaiEwKZoGmFjNpNWNFbnsQc2AUCkNTyTkIrYvCEAOy5OwYXY57O99-rSFEVbtgoKp0A-06KCFSTkk2gOkIGt-G4MGqrv9f-40iWA2-1CBDDTKUFOrPl8L92Pl2_7qoodwNbQX1_Yuxb3Wr9Lt3Qa1eKSYMk5Sy_m5P3I0E9Bq-HXgVjIPGQOk8mKjK1v3_wi8HtoLW</recordid><startdate>1987</startdate><enddate>1987</enddate><creator>Liberski, P.P.</creator><general>Elsevier Ltd</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1987</creationdate><title>Astrocytic reaction in experimental scrapie in hamsters</title><author>Liberski, P.P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c381t-f8a96744f869c2b76873fe24f038fa33b9fc3805e32ebc24855e7aabbc1ce8d53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Animals</topic><topic>astrocytes</topic><topic>Astrocytes - cytology</topic><topic>Astrocytes - ultrastructure</topic><topic>Brain - pathology</topic><topic>Brain - ultrastructure</topic><topic>Cricetinae</topic><topic>Female</topic><topic>gliocytosis</topic><topic>hamsters</topic><topic>hyperplasia</topic><topic>hypertrophy</topic><topic>Male</topic><topic>nervous system diseases</topic><topic>neurons</topic><topic>PrPSc proteins</topic><topic>scrapie</topic><topic>Scrapie - pathology</topic><topic>strains</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liberski, P.P.</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of comparative pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liberski, P.P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Astrocytic reaction in experimental scrapie in hamsters</atitle><jtitle>Journal of comparative pathology</jtitle><addtitle>J Comp Pathol</addtitle><date>1987</date><risdate>1987</risdate><volume>97</volume><issue>1</issue><spage>73</spage><epage>78</epage><pages>73-78</pages><issn>0021-9975</issn><eissn>1532-3129</eissn><abstract>Severe glial reaction (gliocytosis) in hamsters infected with the 263K strain of scrapie is described. Glicytosis is an extremely rare phenomenon in scrapie-affected mice. In hamsters, however, it forms an important and stable feature of the neuropathology. Both astrocytic hyperplasia and hypertrophy are described. The author discusses briefly the possible contribution of the scrapie agent and of the host used in the experiments described here to the development of glial changes.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>3558905</pmid><doi>10.1016/0021-9975(87)90129-0</doi><tpages>6</tpages></addata></record> |
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| ispartof | Journal of comparative pathology, 1987, Vol.97 (1), p.73-78 |
| issn | 0021-9975 1532-3129 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals astrocytes Astrocytes - cytology Astrocytes - ultrastructure Brain - pathology Brain - ultrastructure Cricetinae Female gliocytosis hamsters hyperplasia hypertrophy Male nervous system diseases neurons PrPSc proteins scrapie Scrapie - pathology strains |
| title | Astrocytic reaction in experimental scrapie in hamsters |
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