Heat Shock Factor-1 and the Heat Shock Cognate 70 Protein Associate in High Molecular Weight Complexes in the Cytoplasm of NIH-3T3 Cells

Interaction of heat shock transcription factor-1 (HSF-1) with the seventy kilodalton heat shock cognate protein (HSC70) was examined in NIH 3T3 cells. HSF-1 was found in the cytoplasm of non-stressed cells associated with HSC70 in large (Mr 400-500,000) complexes. After heat shock, HSF-1 became conc...

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Veröffentlicht in:	Biochemical and biophysical research communications 1995-08, Vol.213 (1), p.1-6
Hauptverfasser:	Nunes, S.L., Calderwood, S.K.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Cell Nucleus - metabolism Cytoplasm - metabolism DNA-Binding Proteins - isolation & purification DNA-Binding Proteins - metabolism Heat Shock Transcription Factors Hot Temperature HSP70 Heat-Shock Proteins - isolation & purification HSP70 Heat-Shock Proteins - metabolism Humans Mice Molecular Weight Protein Binding Recombinant Proteins - isolation & purification Recombinant Proteins - metabolism Transcription Factors - isolation & purification Transcription Factors - metabolism
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