Impact of a thrombolysis research trial on time to treatment for acute myocardial infarction in the emergency department
Because time to treatment in AMI is a critical factor in long-term outcome, it is important that complex trials designed to improve reperfusion therapy do not delay the time to treatment. Participation in the TIMI 5 trial did not significantly prolong our door-to-needle time. These results indicate...
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| Veröffentlicht in: | The American journal of cardiology 1995-08, Vol.76 (5), p.396-398 |
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| container_end_page | 398 |
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| container_issue | 5 |
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| container_title | The American journal of cardiology |
| container_volume | 76 |
| creator | Boisjolie, Charlene R. Sharkey, Scott W. Cannon, Christopher P. Brunette, Doug Haugland, J.Mark Thatcher, Jackson L. Henry, Timothy D. |
| description | Because time to treatment in AMI is a critical factor in long-term outcome, it is important that complex trials designed to improve reperfusion therapy do not delay the time to treatment. Participation in the TIMI 5 trial did not significantly prolong our door-to-needle time. These results indicate that, if done carefully, complex, labor-intensive studies can be performed within a reasonable time limit. Care should be taken to design protocols incorporating easy drug preparation, informed consent by the ED, and efficiency of trial initiation. |
| doi_str_mv | 10.1016/S0002-9149(99)80108-8 |
| format | Article |
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| identifier | ISSN: 0002-9149 |
| ispartof | The American journal of cardiology, 1995-08, Vol.76 (5), p.396-398 |
| issn | 0002-9149 1879-1913 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Biological and medical sciences Cardiology. Vascular system Cardiovascular disease Clinical Trials as Topic Coronary heart disease Drug therapy Electrocardiography Emergency Service, Hospital Heart Heparin - therapeutic use Hirudin Therapy Humans Italy Medical research Medical sciences Myocardial Infarction - diagnosis Myocardial Infarction - drug therapy Streptokinase - therapeutic use Thrombolytic Therapy Time Factors United States |
| title | Impact of a thrombolysis research trial on time to treatment for acute myocardial infarction in the emergency department |
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