Recurring Local Sequence Motifs in Proteins

We describe a completely automated approach to identifying local sequence motifs that transcend protein family boundaries. Cluster analysis is used to identify recurring patterns of variation at single positions and in short segments of contiguous positions in multiple sequence alignments for a non-...

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Veröffentlicht in:	Journal of molecular biology 1995-08, Vol.251 (1), p.176-187
Hauptverfasser:	Han, Karen F., Baker, David
Format:	Artikel
Sprache:	eng
Schlagworte:	amino acid sequences Cluster Analysis Helix-Loop-Helix Motifs multiple sequence alignments prediction Protein Conformation protein structure prediction proteins Proteins - chemistry sequence alignment Sequence Alignment - methods sequence comparison Sequence Homology, Amino Acid sequence motifs Statistics as Topic structure substitution matrices
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