SPECT Imaging of Fluorine-18
The objective of this work was to determine the potential clinical usefulness of SPECT to image 511-keV annihilation photons. A triple-headed gamma camera equipped with ultra-high-energy collimators was used to image 18F. Sensitivity measurements were carried out and the FWHM and FWTM were determine...
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| Veröffentlicht in: | The Journal of nuclear medicine (1978) 1995-08, Vol.36 (8), p.1472-1475 |
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| container_title | The Journal of nuclear medicine (1978) |
| container_volume | 36 |
| creator | Leichner, Peter K Morgan, Hugh T Holdeman, Karen P Harrison, Katherine A Valentino, Frank Lexa, Roger Kelly, Richard F Hawkins, William G Dalrymple, Glenn V |
| description | The objective of this work was to determine the potential clinical usefulness of SPECT to image 511-keV annihilation photons.
A triple-headed gamma camera equipped with ultra-high-energy collimators was used to image 18F. Sensitivity measurements were carried out and the FWHM and FWTM were determined in air and for a unit-density scattering medium. Additionally, tomographic phantom studies were acquired to evaluate image quality.
The sensitivities of the three cameras were, for all practical purposes, identical. At a source-to-collimator distance of 100 mm, the FWHM and FWTM were 13 and 29 mm, respectively. A tomographic phantom study demonstrated that spheres with a diameter of 20 mm were well resolved when filled with 18F activity and placed inside a water-filled phantom.
The triple-headed SPECT camera in this investigation is a practical means of acquiring tomographic 18F images. The reconstructed slices were of sufficient quality to be of value in some clinical studies. |
| format | Article |
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A triple-headed gamma camera equipped with ultra-high-energy collimators was used to image 18F. Sensitivity measurements were carried out and the FWHM and FWTM were determined in air and for a unit-density scattering medium. Additionally, tomographic phantom studies were acquired to evaluate image quality.
The sensitivities of the three cameras were, for all practical purposes, identical. At a source-to-collimator distance of 100 mm, the FWHM and FWTM were 13 and 29 mm, respectively. A tomographic phantom study demonstrated that spheres with a diameter of 20 mm were well resolved when filled with 18F activity and placed inside a water-filled phantom.
The triple-headed SPECT camera in this investigation is a practical means of acquiring tomographic 18F images. The reconstructed slices were of sufficient quality to be of value in some clinical studies.</description><identifier>ISSN: 0161-5505</identifier><identifier>EISSN: 1535-5667</identifier><identifier>PMID: 7629597</identifier><language>eng</language><publisher>Reston, VA: Soc Nuclear Med</publisher><subject>Biological and medical sciences ; Fluorine Radioisotopes ; Gamma Cameras ; Humans ; Image Processing, Computer-Assisted ; Investigative techniques, diagnostic techniques (general aspects) ; Medical sciences ; Miscellaneous. Technology ; Models, Structural ; Radionuclide investigations ; Sensitivity and Specificity ; Tomography, Emission-Computed, Single-Photon - instrumentation ; Tomography, Emission-Computed, Single-Photon - methods</subject><ispartof>The Journal of nuclear medicine (1978), 1995-08, Vol.36 (8), p.1472-1475</ispartof><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3618376$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7629597$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Leichner, Peter K</creatorcontrib><creatorcontrib>Morgan, Hugh T</creatorcontrib><creatorcontrib>Holdeman, Karen P</creatorcontrib><creatorcontrib>Harrison, Katherine A</creatorcontrib><creatorcontrib>Valentino, Frank</creatorcontrib><creatorcontrib>Lexa, Roger</creatorcontrib><creatorcontrib>Kelly, Richard F</creatorcontrib><creatorcontrib>Hawkins, William G</creatorcontrib><creatorcontrib>Dalrymple, Glenn V</creatorcontrib><title>SPECT Imaging of Fluorine-18</title><title>The Journal of nuclear medicine (1978)</title><addtitle>J Nucl Med</addtitle><description>The objective of this work was to determine the potential clinical usefulness of SPECT to image 511-keV annihilation photons.
A triple-headed gamma camera equipped with ultra-high-energy collimators was used to image 18F. Sensitivity measurements were carried out and the FWHM and FWTM were determined in air and for a unit-density scattering medium. Additionally, tomographic phantom studies were acquired to evaluate image quality.
The sensitivities of the three cameras were, for all practical purposes, identical. At a source-to-collimator distance of 100 mm, the FWHM and FWTM were 13 and 29 mm, respectively. A tomographic phantom study demonstrated that spheres with a diameter of 20 mm were well resolved when filled with 18F activity and placed inside a water-filled phantom.
The triple-headed SPECT camera in this investigation is a practical means of acquiring tomographic 18F images. The reconstructed slices were of sufficient quality to be of value in some clinical studies.</description><subject>Biological and medical sciences</subject><subject>Fluorine Radioisotopes</subject><subject>Gamma Cameras</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Miscellaneous. Technology</subject><subject>Models, Structural</subject><subject>Radionuclide investigations</subject><subject>Sensitivity and Specificity</subject><subject>Tomography, Emission-Computed, Single-Photon - instrumentation</subject><subject>Tomography, Emission-Computed, Single-Photon - methods</subject><issn>0161-5505</issn><issn>1535-5667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9z0tLAzEUhuEgSq3Vf6DQhehqIJfJyZmllFYLBQW7D5lM0qbMpSYdxH_vSAdXZ_E9vHAuyJRJITMJoC7JlDJgmZRUXpOblA6UUkDECZko4IUs1JTcf34sF9v5ujG70O7mnZ-v6r6LoXUZw1ty5U2d3N14Z2S7Wm4Xb9nm_XW9eNlke4b8lHFJkVtKRWl8AUCpcZ5BpZDnhfdWlUi5YGBNrqj3JVDrC547RFlVzJRiRp7O2WPsvnqXTroJybq6Nq3r-qSVygVKhgN8GGFfNq7SxxgaE3_0-M2wP467SdbUPprWhvTPBAwNBQN7PrN92O2_Q3S67W3tTPxrHtpGgEbNcsXFL3m4XiI</recordid><startdate>199508</startdate><enddate>199508</enddate><creator>Leichner, Peter K</creator><creator>Morgan, Hugh T</creator><creator>Holdeman, Karen P</creator><creator>Harrison, Katherine A</creator><creator>Valentino, Frank</creator><creator>Lexa, Roger</creator><creator>Kelly, Richard F</creator><creator>Hawkins, William G</creator><creator>Dalrymple, Glenn V</creator><general>Soc Nuclear Med</general><general>Society of Nuclear Medicine</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199508</creationdate><title>SPECT Imaging of Fluorine-18</title><author>Leichner, Peter K ; Morgan, Hugh T ; Holdeman, Karen P ; Harrison, Katherine A ; Valentino, Frank ; Lexa, Roger ; Kelly, Richard F ; Hawkins, William G ; Dalrymple, Glenn V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h182t-25082c003baf96600aef16d78249ffc7b802316ca470ffb60cf924e885dd1ab3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Biological and medical sciences</topic><topic>Fluorine Radioisotopes</topic><topic>Gamma Cameras</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Medical sciences</topic><topic>Miscellaneous. Technology</topic><topic>Models, Structural</topic><topic>Radionuclide investigations</topic><topic>Sensitivity and Specificity</topic><topic>Tomography, Emission-Computed, Single-Photon - instrumentation</topic><topic>Tomography, Emission-Computed, Single-Photon - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leichner, Peter K</creatorcontrib><creatorcontrib>Morgan, Hugh T</creatorcontrib><creatorcontrib>Holdeman, Karen P</creatorcontrib><creatorcontrib>Harrison, Katherine A</creatorcontrib><creatorcontrib>Valentino, Frank</creatorcontrib><creatorcontrib>Lexa, Roger</creatorcontrib><creatorcontrib>Kelly, Richard F</creatorcontrib><creatorcontrib>Hawkins, William G</creatorcontrib><creatorcontrib>Dalrymple, Glenn V</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of nuclear medicine (1978)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leichner, Peter K</au><au>Morgan, Hugh T</au><au>Holdeman, Karen P</au><au>Harrison, Katherine A</au><au>Valentino, Frank</au><au>Lexa, Roger</au><au>Kelly, Richard F</au><au>Hawkins, William G</au><au>Dalrymple, Glenn V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>SPECT Imaging of Fluorine-18</atitle><jtitle>The Journal of nuclear medicine (1978)</jtitle><addtitle>J Nucl Med</addtitle><date>1995-08</date><risdate>1995</risdate><volume>36</volume><issue>8</issue><spage>1472</spage><epage>1475</epage><pages>1472-1475</pages><issn>0161-5505</issn><eissn>1535-5667</eissn><abstract>The objective of this work was to determine the potential clinical usefulness of SPECT to image 511-keV annihilation photons.
A triple-headed gamma camera equipped with ultra-high-energy collimators was used to image 18F. Sensitivity measurements were carried out and the FWHM and FWTM were determined in air and for a unit-density scattering medium. Additionally, tomographic phantom studies were acquired to evaluate image quality.
The sensitivities of the three cameras were, for all practical purposes, identical. At a source-to-collimator distance of 100 mm, the FWHM and FWTM were 13 and 29 mm, respectively. A tomographic phantom study demonstrated that spheres with a diameter of 20 mm were well resolved when filled with 18F activity and placed inside a water-filled phantom.
The triple-headed SPECT camera in this investigation is a practical means of acquiring tomographic 18F images. The reconstructed slices were of sufficient quality to be of value in some clinical studies.</abstract><cop>Reston, VA</cop><pub>Soc Nuclear Med</pub><pmid>7629597</pmid><tpages>4</tpages></addata></record> |
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| identifier | ISSN: 0161-5505 |
| ispartof | The Journal of nuclear medicine (1978), 1995-08, Vol.36 (8), p.1472-1475 |
| issn | 0161-5505 1535-5667 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77438518 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Biological and medical sciences Fluorine Radioisotopes Gamma Cameras Humans Image Processing, Computer-Assisted Investigative techniques, diagnostic techniques (general aspects) Medical sciences Miscellaneous. Technology Models, Structural Radionuclide investigations Sensitivity and Specificity Tomography, Emission-Computed, Single-Photon - instrumentation Tomography, Emission-Computed, Single-Photon - methods |
| title | SPECT Imaging of Fluorine-18 |
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