The effect of hypophysectomy, ACTH fragments and thalamic lesions upon kindled epilepsy

Hypophysectomized rats showed aberrant and retarded rates of kindled epilepsy. In hypophysectomized rats administered adrenocorticotropic hormone (ACTH) subunits ACTH 4–10 and ACTH 1–24, the normal kindling pattern was restored. However, in hypophysectomized animals which also had lesions of the tha...

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Veröffentlicht in:	Brain research 1987-02, Vol.403 (1), p.96-104
Hauptverfasser:	Rogers, Oscar L., Jackson, William J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Glands - pathology Adrenal Glands - physiopathology Adrenocorticotropic hormone Adrenocorticotropic Hormone - analogs & derivatives Adrenocorticotropic Hormone - pharmacology Amygdala Animals Behavior, Animal - physiology Biological and medical sciences Cosyntropin - pharmacology Electroencephalography Epilepsy - physiopathology Hypophysectomy Kindled epilepsy Kindling, Neurologic - drug effects Learning Male Medical sciences Nervous system involvement in other diseases. Miscellaneous Neurology Nucleus parafascicularis Organ Size Peptide Fragments - pharmacology Rats Rats, Inbred Strains Thalamus - pathology Thalamus - physiopathology
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