Expression of p53 oncoprotein in non-small-cell lung cancer: a favorable prognostic factor

Mutation of the p53 gene is one of the most common genetic abnormalities found in lung cancer. The purpose of this study was to evaluate the prognostic value of p53 oncoprotein expression in patients with non-small-cell lung cancer (NSCLC). We studied 156 resected primary NSCLCs by the immunohistoch...

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Veröffentlicht in:	Journal of clinical oncology 1995-08, Vol.13 (8), p.1893-1903
Hauptverfasser:	JIN SOO LEE, YOON, A, KALAPURAKAL, S. K, RO, J. Y, LEE, J. J, TU, N, HITTELMAN, W. N, HONG, W. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adult Aged Biological and medical sciences Carcinoma, Large Cell - metabolism Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Squamous Cell - metabolism Chi-Square Distribution Female Humans Immunohistochemistry Lung Neoplasms - metabolism Lung Neoplasms - mortality Lung Neoplasms - pathology Lymph Nodes - pathology Lymphatic Metastasis Male Medical sciences Middle Aged Pneumology Prognosis Regression Analysis Survival Rate Tumor Suppressor Protein p53 - metabolism Tumors of the respiratory system and mediastinum
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