The Proteins Elafin, Filaggrin, Keratin Intermediate Filaments, Loricrin, and Small Proline-rich Proteins 1 and 2 Are Isodipeptide Cross-linked Components of the Human Epidermal Cornified Cell Envelope

The cornified cell envelope (CE) is a 15-nm thick layer of insoluble protein deposited on the intracellular side of the cell membrane of terminally differentiated stratified squamous epithelia. The CE is thought to consist of a complex amalgam of proteins cross-linked by isodipeptide bonds formed by...

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Veröffentlicht in:	The Journal of biological chemistry 1995-07, Vol.270 (30), p.17702-17711
Hauptverfasser:	Steinert, P M, Marekov, L N
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Chromatography, High Pressure Liquid Cornified Envelope Proline-Rich Proteins Cytoplasm - chemistry Epidermis - chemistry Humans Intermediate Filament Proteins - chemistry Intermediate Filament Proteins - isolation & purification Intermediate Filaments - chemistry Keratins - chemistry Keratins - isolation & purification Membrane Proteins - chemistry Membrane Proteins - isolation & purification Models, Molecular Molecular Sequence Data Peptides - chemistry Peptides - isolation & purification Proline-Rich Protein Domains Proteinase Inhibitory Proteins, Secretory Proteins Serine Proteinase Inhibitors - chemistry Serine Proteinase Inhibitors - isolation & purification
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