Specific A·T DNA sequence binding of RP-HPLC purified HMG-I

HMG-I (α-protein) is a high mobility group protein which r. ognizes and binds specifically to A·T rich double stranded DNA. We have investigated, by electrophoretic shift assays and DNase I footprinting, the ability of reverse-phase high performance liquid chromatography purified HMG-I to bind to sp...

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Veröffentlicht in:	Biochemical and biophysical research communications 1987-02, Vol.143 (1), p.260-265
Hauptverfasser:	Elton, Terry S., Nissen, Mark S., Reeves, Raymond
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine Animals Applied sciences Base Sequence Chromatography, High Pressure Liquid Deoxyribonuclease I DNA - metabolism Exact sciences and technology High Mobility Group Proteins - isolation & purification High Mobility Group Proteins - metabolism Leukemia, Erythroblastic, Acute - metabolism Leukemia, Experimental - metabolism Mice Other techniques and industries Protein Binding Thymine
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