Definition of the critical cellular components which distinguish between hormone and antihormone activated progesterone receptor

The steroid hormone progesterone is a key modulator of the cellular processes associated with the maintenance and development of female reproductive function. The biological activity of this hormone is mediated by specific nuclear receptors located in target cell nuclei which upon activation are cap...

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Veröffentlicht in:	Journal of steroid biochemistry and molecular biology 1995-06, Vol.53 (1), p.487-495
Hauptverfasser:	Clemm, David L., Macy, Bryan L., Santiso-Mere, Dolores, McDonnell, Donald P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences DNA-Binding Proteins - physiology Gene Expression Regulation Hormones. Endocrine system Humans Macromolecular Substances Medical sciences Mifepristone - analogs & derivatives Mifepristone - pharmacology Pharmacology. Drug treatments Progesterone - chemistry Promoter Regions, Genetic Receptors, Progesterone - antagonists & inhibitors Receptors, Progesterone - classification Receptors, Progesterone - physiology Receptors, Steroid - physiology Repressor Proteins Signal Transduction Structure-Activity Relationship Transcription, Genetic Transcriptional Activation
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