Role of cardiopulmonary mechanoreceptors in the postural regulation of renin
To change the stretch on cardiopulmonary mechanoreceptors, large shifts of blood in the capacity space were elicited by tilting and by exerting positive lower body pressure in the tilted position. Twelve volunteers underwent invasive hemodynamic studies and in 10 other subjects cardiac size was dete...
Gespeichert in:
| Veröffentlicht in: | Am. J. Cardiol.; (United States) 1987-04, Vol.59 (8), p.881-886 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 886 |
|---|---|
| container_issue | 8 |
| container_start_page | 881 |
| container_title | Am. J. Cardiol.; (United States) |
| container_volume | 59 |
| creator | Sanchez, Ramiro A. Marco, Enrique J. Oliveri, Carlos Otero, Fernando J. Degrossi, Osvaldo Moledo, Luis I. Julius, Stevo |
| description | To change the stretch on cardiopulmonary mechanoreceptors, large shifts of blood in the capacity space were elicited by tilting and by exerting positive lower body pressure in the tilted position. Twelve volunteers underwent invasive hemodynamic studies and in 10 other subjects cardiac size was determined by radionuclide cardiography. In all 22 subjects tilting caused the expected increase of renin, which was abolished by lower body compression. Decompression caused renin to increase again. Right atrial pressure In invasive studies and end-systolic and end-diastolic counts in noninvasive studies showed a significant and strong negative correlation with renin and norepinephrine levels. Thus, the degree of stretch of the cardiopulmonary mechanoreceptors is a major determinant of reflex regulation of renin release in humans. |
| doi_str_mv | 10.1016/0002-9149(87)91112-X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_osti_</sourceid><recordid>TN_cdi_proquest_miscellaneous_77424653</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>000291498791112X</els_id><sourcerecordid>77424653</sourcerecordid><originalsourceid>FETCH-LOGICAL-c459t-9ab641f1bc98687e022be5af68402156bb23380577adbff229e06fa6fa9c278a3</originalsourceid><addsrcrecordid>eNp9kF1rFTEQhoMo9bT1HygsIqIXq0k2nzcFKbUVDghSoXchm53YyG6yJruC_96s53AuhcAQ5pnhnQehlwR_IJiIjxhj2mrC9Dsl32tCCG0fnqAdUVK3RJPuKdqdkOfovJSf9UsIF2forONMdZjv0P5bGqFJvnE2DyHN6zilaPOfZgL3aGPK4GBeUi5NiM3yCM2cyrJmOzYZfqyjXUKK23iGGOIleubtWODFsV6g759v7q_v2v3X2y_Xn_atY1wvrba9YMST3mkllARMaQ_ceqEYpjVf39OuU5hLaYfee0o1YOFtfdpRqWx3gV4f9tYswRQXlhrWpRjBLUZwLWjHKvT2AM05_VqhLGYKxcE42ghpLUZKRpngXQXZAXQ5lZLBmzmHqTowBJvNtNk0mk2jUdL8M20e6tir4_61n2A4DR3V1v6bY98WZ0efbXShnDDJKRaSVOzqgEEV9jtA3u6B6GAIeTtnSOH_Of4CllWZ8Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>77424653</pqid></control><display><type>article</type><title>Role of cardiopulmonary mechanoreceptors in the postural regulation of renin</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Sanchez, Ramiro A. ; Marco, Enrique J. ; Oliveri, Carlos ; Otero, Fernando J. ; Degrossi, Osvaldo ; Moledo, Luis I. ; Julius, Stevo</creator><creatorcontrib>Sanchez, Ramiro A. ; Marco, Enrique J. ; Oliveri, Carlos ; Otero, Fernando J. ; Degrossi, Osvaldo ; Moledo, Luis I. ; Julius, Stevo ; Hospital Instituto de Cardiologia, Buenos Aires, Argentina</creatorcontrib><description>To change the stretch on cardiopulmonary mechanoreceptors, large shifts of blood in the capacity space were elicited by tilting and by exerting positive lower body pressure in the tilted position. Twelve volunteers underwent invasive hemodynamic studies and in 10 other subjects cardiac size was determined by radionuclide cardiography. In all 22 subjects tilting caused the expected increase of renin, which was abolished by lower body compression. Decompression caused renin to increase again. Right atrial pressure In invasive studies and end-systolic and end-diastolic counts in noninvasive studies showed a significant and strong negative correlation with renin and norepinephrine levels. Thus, the degree of stretch of the cardiopulmonary mechanoreceptors is a major determinant of reflex regulation of renin release in humans.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/0002-9149(87)91112-X</identifier><identifier>PMID: 3548305</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; BLOOD PRESSURE ; BODY ; Cardiac Catheterization ; CARDIOVASCULAR SYSTEM ; COUNTING TECHNIQUES ; ELEMENTS ; Endocrine kidney. Renin-angiotensin-aldosterone system ; ENZYMES ; Female ; Fundamental and applied biological sciences. Psychology ; Gravity Suits ; HEART ; Heart - innervation ; Heart Ventricles - diagnostic imaging ; Hemodynamics ; Humans ; HYDROLASES ; Male ; Mechanoreceptors - physiology ; METALS ; NONSPECIFIC PEPTIDASES ; ORGANS ; PEPTIDE HYDROLASES ; Posture ; Pulmonary Stretch Receptors - physiology ; RADIOISOTOPE SCANNING ; RADIOLOGY AND NUCLEAR MEDICINE ; Radionuclide Imaging ; RENIN ; Renin - blood ; SECRETION ; SIZE ; Space life sciences ; TECHNETIUM ; TRANSITION ELEMENTS 550601 -- Medicine-- Unsealed Radionuclides in Diagnostics ; Vertebrates: endocrinology</subject><ispartof>Am. J. Cardiol.; (United States), 1987-04, Vol.59 (8), p.881-886</ispartof><rights>1987</rights><rights>1988 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c459t-9ab641f1bc98687e022be5af68402156bb23380577adbff229e06fa6fa9c278a3</citedby><cites>FETCH-LOGICAL-c459t-9ab641f1bc98687e022be5af68402156bb23380577adbff229e06fa6fa9c278a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-9149(87)91112-X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,885,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7520671$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3548305$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/6596234$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Sanchez, Ramiro A.</creatorcontrib><creatorcontrib>Marco, Enrique J.</creatorcontrib><creatorcontrib>Oliveri, Carlos</creatorcontrib><creatorcontrib>Otero, Fernando J.</creatorcontrib><creatorcontrib>Degrossi, Osvaldo</creatorcontrib><creatorcontrib>Moledo, Luis I.</creatorcontrib><creatorcontrib>Julius, Stevo</creatorcontrib><creatorcontrib>Hospital Instituto de Cardiologia, Buenos Aires, Argentina</creatorcontrib><title>Role of cardiopulmonary mechanoreceptors in the postural regulation of renin</title><title>Am. J. Cardiol.; (United States)</title><addtitle>Am J Cardiol</addtitle><description>To change the stretch on cardiopulmonary mechanoreceptors, large shifts of blood in the capacity space were elicited by tilting and by exerting positive lower body pressure in the tilted position. Twelve volunteers underwent invasive hemodynamic studies and in 10 other subjects cardiac size was determined by radionuclide cardiography. In all 22 subjects tilting caused the expected increase of renin, which was abolished by lower body compression. Decompression caused renin to increase again. Right atrial pressure In invasive studies and end-systolic and end-diastolic counts in noninvasive studies showed a significant and strong negative correlation with renin and norepinephrine levels. Thus, the degree of stretch of the cardiopulmonary mechanoreceptors is a major determinant of reflex regulation of renin release in humans.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>BLOOD PRESSURE</subject><subject>BODY</subject><subject>Cardiac Catheterization</subject><subject>CARDIOVASCULAR SYSTEM</subject><subject>COUNTING TECHNIQUES</subject><subject>ELEMENTS</subject><subject>Endocrine kidney. Renin-angiotensin-aldosterone system</subject><subject>ENZYMES</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gravity Suits</subject><subject>HEART</subject><subject>Heart - innervation</subject><subject>Heart Ventricles - diagnostic imaging</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>HYDROLASES</subject><subject>Male</subject><subject>Mechanoreceptors - physiology</subject><subject>METALS</subject><subject>NONSPECIFIC PEPTIDASES</subject><subject>ORGANS</subject><subject>PEPTIDE HYDROLASES</subject><subject>Posture</subject><subject>Pulmonary Stretch Receptors - physiology</subject><subject>RADIOISOTOPE SCANNING</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radionuclide Imaging</subject><subject>RENIN</subject><subject>Renin - blood</subject><subject>SECRETION</subject><subject>SIZE</subject><subject>Space life sciences</subject><subject>TECHNETIUM</subject><subject>TRANSITION ELEMENTS 550601 -- Medicine-- Unsealed Radionuclides in Diagnostics</subject><subject>Vertebrates: endocrinology</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF1rFTEQhoMo9bT1HygsIqIXq0k2nzcFKbUVDghSoXchm53YyG6yJruC_96s53AuhcAQ5pnhnQehlwR_IJiIjxhj2mrC9Dsl32tCCG0fnqAdUVK3RJPuKdqdkOfovJSf9UsIF2forONMdZjv0P5bGqFJvnE2DyHN6zilaPOfZgL3aGPK4GBeUi5NiM3yCM2cyrJmOzYZfqyjXUKK23iGGOIleubtWODFsV6g759v7q_v2v3X2y_Xn_atY1wvrba9YMST3mkllARMaQ_ceqEYpjVf39OuU5hLaYfee0o1YOFtfdpRqWx3gV4f9tYswRQXlhrWpRjBLUZwLWjHKvT2AM05_VqhLGYKxcE42ghpLUZKRpngXQXZAXQ5lZLBmzmHqTowBJvNtNk0mk2jUdL8M20e6tir4_61n2A4DR3V1v6bY98WZ0efbXShnDDJKRaSVOzqgEEV9jtA3u6B6GAIeTtnSOH_Of4CllWZ8Q</recordid><startdate>19870401</startdate><enddate>19870401</enddate><creator>Sanchez, Ramiro A.</creator><creator>Marco, Enrique J.</creator><creator>Oliveri, Carlos</creator><creator>Otero, Fernando J.</creator><creator>Degrossi, Osvaldo</creator><creator>Moledo, Luis I.</creator><creator>Julius, Stevo</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>19870401</creationdate><title>Role of cardiopulmonary mechanoreceptors in the postural regulation of renin</title><author>Sanchez, Ramiro A. ; Marco, Enrique J. ; Oliveri, Carlos ; Otero, Fernando J. ; Degrossi, Osvaldo ; Moledo, Luis I. ; Julius, Stevo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c459t-9ab641f1bc98687e022be5af68402156bb23380577adbff229e06fa6fa9c278a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>BLOOD PRESSURE</topic><topic>BODY</topic><topic>Cardiac Catheterization</topic><topic>CARDIOVASCULAR SYSTEM</topic><topic>COUNTING TECHNIQUES</topic><topic>ELEMENTS</topic><topic>Endocrine kidney. Renin-angiotensin-aldosterone system</topic><topic>ENZYMES</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gravity Suits</topic><topic>HEART</topic><topic>Heart - innervation</topic><topic>Heart Ventricles - diagnostic imaging</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>HYDROLASES</topic><topic>Male</topic><topic>Mechanoreceptors - physiology</topic><topic>METALS</topic><topic>NONSPECIFIC PEPTIDASES</topic><topic>ORGANS</topic><topic>PEPTIDE HYDROLASES</topic><topic>Posture</topic><topic>Pulmonary Stretch Receptors - physiology</topic><topic>RADIOISOTOPE SCANNING</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radionuclide Imaging</topic><topic>RENIN</topic><topic>Renin - blood</topic><topic>SECRETION</topic><topic>SIZE</topic><topic>Space life sciences</topic><topic>TECHNETIUM</topic><topic>TRANSITION ELEMENTS 550601 -- Medicine-- Unsealed Radionuclides in Diagnostics</topic><topic>Vertebrates: endocrinology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sanchez, Ramiro A.</creatorcontrib><creatorcontrib>Marco, Enrique J.</creatorcontrib><creatorcontrib>Oliveri, Carlos</creatorcontrib><creatorcontrib>Otero, Fernando J.</creatorcontrib><creatorcontrib>Degrossi, Osvaldo</creatorcontrib><creatorcontrib>Moledo, Luis I.</creatorcontrib><creatorcontrib>Julius, Stevo</creatorcontrib><creatorcontrib>Hospital Instituto de Cardiologia, Buenos Aires, Argentina</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Am. J. Cardiol.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sanchez, Ramiro A.</au><au>Marco, Enrique J.</au><au>Oliveri, Carlos</au><au>Otero, Fernando J.</au><au>Degrossi, Osvaldo</au><au>Moledo, Luis I.</au><au>Julius, Stevo</au><aucorp>Hospital Instituto de Cardiologia, Buenos Aires, Argentina</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of cardiopulmonary mechanoreceptors in the postural regulation of renin</atitle><jtitle>Am. J. Cardiol.; (United States)</jtitle><addtitle>Am J Cardiol</addtitle><date>1987-04-01</date><risdate>1987</risdate><volume>59</volume><issue>8</issue><spage>881</spage><epage>886</epage><pages>881-886</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>To change the stretch on cardiopulmonary mechanoreceptors, large shifts of blood in the capacity space were elicited by tilting and by exerting positive lower body pressure in the tilted position. Twelve volunteers underwent invasive hemodynamic studies and in 10 other subjects cardiac size was determined by radionuclide cardiography. In all 22 subjects tilting caused the expected increase of renin, which was abolished by lower body compression. Decompression caused renin to increase again. Right atrial pressure In invasive studies and end-systolic and end-diastolic counts in noninvasive studies showed a significant and strong negative correlation with renin and norepinephrine levels. Thus, the degree of stretch of the cardiopulmonary mechanoreceptors is a major determinant of reflex regulation of renin release in humans.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3548305</pmid><doi>10.1016/0002-9149(87)91112-X</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9149 |
| ispartof | Am. J. Cardiol.; (United States), 1987-04, Vol.59 (8), p.881-886 |
| issn | 0002-9149 1879-1913 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77424653 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adolescent Adult Biological and medical sciences BLOOD PRESSURE BODY Cardiac Catheterization CARDIOVASCULAR SYSTEM COUNTING TECHNIQUES ELEMENTS Endocrine kidney. Renin-angiotensin-aldosterone system ENZYMES Female Fundamental and applied biological sciences. Psychology Gravity Suits HEART Heart - innervation Heart Ventricles - diagnostic imaging Hemodynamics Humans HYDROLASES Male Mechanoreceptors - physiology METALS NONSPECIFIC PEPTIDASES ORGANS PEPTIDE HYDROLASES Posture Pulmonary Stretch Receptors - physiology RADIOISOTOPE SCANNING RADIOLOGY AND NUCLEAR MEDICINE Radionuclide Imaging RENIN Renin - blood SECRETION SIZE Space life sciences TECHNETIUM TRANSITION ELEMENTS 550601 -- Medicine-- Unsealed Radionuclides in Diagnostics Vertebrates: endocrinology |
| title | Role of cardiopulmonary mechanoreceptors in the postural regulation of renin |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T11%3A34%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_osti_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Role%20of%20cardiopulmonary%20mechanoreceptors%20in%20the%20postural%20regulation%20of%20renin&rft.jtitle=Am.%20J.%20Cardiol.;%20(United%20States)&rft.au=Sanchez,%20Ramiro%20A.&rft.aucorp=Hospital%20Instituto%20de%20Cardiologia,%20Buenos%20Aires,%20Argentina&rft.date=1987-04-01&rft.volume=59&rft.issue=8&rft.spage=881&rft.epage=886&rft.pages=881-886&rft.issn=0002-9149&rft.eissn=1879-1913&rft.coden=AJCDAG&rft_id=info:doi/10.1016/0002-9149(87)91112-X&rft_dat=%3Cproquest_osti_%3E77424653%3C/proquest_osti_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=77424653&rft_id=info:pmid/3548305&rft_els_id=000291498791112X&rfr_iscdi=true |