Timing and quantification of bone loss in cardiac transplant recipients
To evaluate osteopenic bone disease in heart transplant patients, we prospectively measured bone mineral density (BMD) in 33 consecutive male recipients before hospital discharge and 1 year later, using dual photon absorptiometry. At hospital discharge BMD measurement at the lumbar spine was only 90...
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| Veröffentlicht in: | Transplant international 1995-05, Vol.8 (3), p.196-200 |
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| container_title | Transplant international |
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| creator | Cleemput, Johan Van Daenen, Wim Nijs, Jos Geusens, Piet Dequeker, Jan Vanhaecke, Johan |
| description | To evaluate osteopenic bone disease in heart transplant patients, we prospectively measured bone mineral density (BMD) in 33 consecutive male recipients before hospital discharge and 1 year later, using dual photon absorptiometry. At hospital discharge BMD measurement at the lumbar spine was only 90% of that expected in healthy age‐ and sex‐matched controls (P= 0.005). One year later BMD had further decreased by 8.5% at the lumbar spine and by 10.4% at the femoral neck (P= 0.0001). Five patients suffered vertebral compression fractures during the 1st postoperative year. Our results indicate that osteopenia of the lumbar spine is already present at the time of hospital discharge after transplantation and that further bone loss occurs at a considerable rate during the 1st postoperative year at the lumbar spine and at the femoral neck. |
| doi_str_mv | 10.1111/j.1432-2277.1995.tb01503.x |
| format | Article |
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At hospital discharge BMD measurement at the lumbar spine was only 90% of that expected in healthy age‐ and sex‐matched controls (P= 0.005). One year later BMD had further decreased by 8.5% at the lumbar spine and by 10.4% at the femoral neck (P= 0.0001). Five patients suffered vertebral compression fractures during the 1st postoperative year. Our results indicate that osteopenia of the lumbar spine is already present at the time of hospital discharge after transplantation and that further bone loss occurs at a considerable rate during the 1st postoperative year at the lumbar spine and at the femoral neck.</description><identifier>ISSN: 0934-0874</identifier><identifier>EISSN: 1432-2277</identifier><identifier>DOI: 10.1111/j.1432-2277.1995.tb01503.x</identifier><identifier>PMID: 7626179</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Diseases of the osteoarticular system ; Graft Rejection - prevention & control ; Heart Transplantation ; Humans ; Immunosuppressive Agents - adverse effects ; Male ; Medical sciences ; Middle Aged ; Osteoporosis - etiology ; Osteoporosis - physiopathology ; Osteoporosis. Osteomalacia. Paget disease ; osteoporosis. 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At hospital discharge BMD measurement at the lumbar spine was only 90% of that expected in healthy age‐ and sex‐matched controls (P= 0.005). One year later BMD had further decreased by 8.5% at the lumbar spine and by 10.4% at the femoral neck (P= 0.0001). Five patients suffered vertebral compression fractures during the 1st postoperative year. Our results indicate that osteopenia of the lumbar spine is already present at the time of hospital discharge after transplantation and that further bone loss occurs at a considerable rate during the 1st postoperative year at the lumbar spine and at the femoral neck.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Diseases of the osteoarticular system</subject><subject>Graft Rejection - prevention & control</subject><subject>Heart Transplantation</subject><subject>Humans</subject><subject>Immunosuppressive Agents - adverse effects</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Osteoporosis - etiology</subject><subject>Osteoporosis - physiopathology</subject><subject>Osteoporosis. Osteomalacia. Paget disease</subject><subject>osteoporosis. Osteoporosis</subject><subject>Time Factors</subject><issn>0934-0874</issn><issn>1432-2277</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkF1LwzAUhoMoc05_ghBEvGtNk7RpvBBk-DEYCDKvQ5omktGmXdPi9u9NWdm9uQnhfU7OywPAXYLiJJzHbZxQgiOMGYsTztO4L1CSIhLvz8D8FJ2DOeKERihn9BJceb9FCOE8RTMwYxnOEsbn4H1ja-t-oHQl3A3S9dZYJXvbONgYWDROw6rxHloHlexKKxXsO-l8WwUWdlrZ1mrX-2twYWTl9c10L8D32-tm-RGtP99Xy5d1pAhBWVSQ0IFqlEqdcUQlJnmJKNZYGVxoYmRZFiblKcGaK1OUJSd5YVgeXlQRbMgCPBz_bbtmN2jfi9p6patQRzeDF4xRTHGWBvDpCKou9O-0EW1na9kdRILEaFFsxahKjKrEaFFMFsU-DN9OW4ai1uVpdNIW8vspl17JygQjyvoTRmjOKSMBez5iv7bSh38UEJuvVcIz8geM-I-r</recordid><startdate>199505</startdate><enddate>199505</enddate><creator>Cleemput, Johan Van</creator><creator>Daenen, Wim</creator><creator>Nijs, Jos</creator><creator>Geusens, Piet</creator><creator>Dequeker, Jan</creator><creator>Vanhaecke, Johan</creator><general>Blackwell Publishing Ltd</general><general>Blackwell Publishing</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199505</creationdate><title>Timing and quantification of bone loss in cardiac transplant recipients</title><author>Cleemput, Johan Van ; Daenen, Wim ; Nijs, Jos ; Geusens, Piet ; Dequeker, Jan ; Vanhaecke, Johan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3306-b30004e05ae6904a238d042e2cf2be3faddbf59532e9cfbdd938bf78e9c4c32f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Diseases of the osteoarticular system</topic><topic>Graft Rejection - prevention & control</topic><topic>Heart Transplantation</topic><topic>Humans</topic><topic>Immunosuppressive Agents - adverse effects</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Osteoporosis - etiology</topic><topic>Osteoporosis - physiopathology</topic><topic>Osteoporosis. Osteomalacia. Paget disease</topic><topic>osteoporosis. Osteoporosis</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cleemput, Johan Van</creatorcontrib><creatorcontrib>Daenen, Wim</creatorcontrib><creatorcontrib>Nijs, Jos</creatorcontrib><creatorcontrib>Geusens, Piet</creatorcontrib><creatorcontrib>Dequeker, Jan</creatorcontrib><creatorcontrib>Vanhaecke, Johan</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Transplant international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cleemput, Johan Van</au><au>Daenen, Wim</au><au>Nijs, Jos</au><au>Geusens, Piet</au><au>Dequeker, Jan</au><au>Vanhaecke, Johan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Timing and quantification of bone loss in cardiac transplant recipients</atitle><jtitle>Transplant international</jtitle><addtitle>Transpl Int</addtitle><date>1995-05</date><risdate>1995</risdate><volume>8</volume><issue>3</issue><spage>196</spage><epage>200</epage><pages>196-200</pages><issn>0934-0874</issn><eissn>1432-2277</eissn><abstract>To evaluate osteopenic bone disease in heart transplant patients, we prospectively measured bone mineral density (BMD) in 33 consecutive male recipients before hospital discharge and 1 year later, using dual photon absorptiometry. At hospital discharge BMD measurement at the lumbar spine was only 90% of that expected in healthy age‐ and sex‐matched controls (P= 0.005). One year later BMD had further decreased by 8.5% at the lumbar spine and by 10.4% at the femoral neck (P= 0.0001). Five patients suffered vertebral compression fractures during the 1st postoperative year. Our results indicate that osteopenia of the lumbar spine is already present at the time of hospital discharge after transplantation and that further bone loss occurs at a considerable rate during the 1st postoperative year at the lumbar spine and at the femoral neck.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>7626179</pmid><doi>10.1111/j.1432-2277.1995.tb01503.x</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0934-0874 |
| ispartof | Transplant international, 1995-05, Vol.8 (3), p.196-200 |
| issn | 0934-0874 1432-2277 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77424265 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Aged Biological and medical sciences Diseases of the osteoarticular system Graft Rejection - prevention & control Heart Transplantation Humans Immunosuppressive Agents - adverse effects Male Medical sciences Middle Aged Osteoporosis - etiology Osteoporosis - physiopathology Osteoporosis. Osteomalacia. Paget disease osteoporosis. Osteoporosis Time Factors |
| title | Timing and quantification of bone loss in cardiac transplant recipients |
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