Radiolocalization of pancreatic carcinoma xenografts in nude mice with radiolabeled chimeric Fab fragments of anti-carcinoembryonic antigen monoclonal antibody A10

Recombinant mouse-human chimeric Fab fragments of anti-carcinoembryonic antigen monoclonal antibody (MAb) A10 react with various GI carcinomas. We tested radiolocalization of pancreatic carcinoma xenografts in nude mice using radiolabeled chimeric A10 Fab fragments, comparing them with murine Fab fr...

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Veröffentlicht in:	Pancreas 1995-04, Vol.10 (3), p.258-264
Hauptverfasser:	KAMIGAKI, T, YAMAMOTO, M, OHYANAGI, H, SAITOH, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - pharmacokinetics Antibody Specificity Autoradiography Biological and medical sciences Carcinoembryonic Antigen - immunology Female Gastroenterology. Liver. Pancreas. Abdomen Humans Immunoglobulin Fab Fragments - metabolism Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Mice Mice, Inbred BALB C Mice, Nude Neoplasm Transplantation Pancreatic Neoplasms - diagnostic imaging Pancreatic Neoplasms - immunology Pancreatic Neoplasms - metabolism Radioimmunodetection - methods Recombinant Fusion Proteins - immunology Recombinant Fusion Proteins - pharmacokinetics Tissue Distribution Transplantation, Heterologous Tumor Cells, Cultured Tumors
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