EGFR gene amplification ‐ rearrangement in human glioblastomas

Immunostaining using an affinity‐purified rabbit polyclonal antibody against the extracellular domain of the epidermal‐growth‐factor receptor (EGFR) showed over‐expression occurring in a fraction of tumor cells in 17 out of 18 human glioblastomas and in a majority of cells in 7 of the 18. Southern‐b...

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Veröffentlicht in:	International journal of cancer 1995-07, Vol.62 (2), p.145-148
Hauptverfasser:	Schwechheimer, Karl, Huang, Su, Cavenee, Webster K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Brain Neoplasms - genetics Cell Line DNA Primers - chemistry DNA, Neoplasm - genetics ErbB Receptors - genetics Gene Amplification Gene Expression Regulation, Neoplastic Gene Rearrangement Glioblastoma - genetics Humans Medical sciences Molecular Sequence Data Neurology RNA Splicing RNA, Neoplasm - genetics Tumors of the nervous system. Phacomatoses
Online-Zugang:	Volltext
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