Molecular characterization of a (1;10)(p22;q21) constitutional translocation from a patient with neuroblastoma

A constitutional t(1;10)(p22;q21) from a patient with stage IVS neuroblastoma has been isolated in somatic cell hybrids and the position of the breakpoints analyzed. On chromosome 1 the breakpoint lies in a 4-Mbp region flanked by minisatellite marker D1S234 and by D1S188, which lies in the region o...

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Veröffentlicht in:	Cancer genetics and cytogenetics 1995-06, Vol.81 (2), p.151-157
Hauptverfasser:	Scott Mead, R., Cowell, John K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences breakpoints Chromosome 1 Chromosome 10 Chromosome Mapping Chromosomes, Human, Pair 1 - genetics Chromosomes, Human, Pair 10 - genetics DNA Probes DNA, Neoplasm - analysis Female Humans Infant man Medical sciences Molecular Sequence Data neuroblastoma Neuroblastoma - genetics Neurology Retroperitoneal Neoplasms - genetics translocation Translocation, Genetic - genetics Tumors of the nervous system. Phacomatoses
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