Dobutamine-induced ST-segment elevation in patients with healed myocardial infarction: a marker of myocardial viability
The purpose of this study was to determine the significance of transient ST-segment elevation during dobutamine infusions in patients with healed Q wave myocardial infarction. Twenty-seven patients with previous Q wave myocardial infarction were studied prospectively with dobutamine-thallium-201 sin...
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| Veröffentlicht in: | Journal of electrocardiology 1995-04, Vol.28 (2), p.91-97 |
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| container_title | Journal of electrocardiology |
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| creator | LEKAKIS, J. P PRASSOPOULOS, V KOSTAMIS, P MOULOPOULOS, S |
| description | The purpose of this study was to determine the significance of transient ST-segment elevation during dobutamine infusions in patients with healed Q wave myocardial infarction. Twenty-seven patients with previous Q wave myocardial infarction were studied prospectively with dobutamine-thallium-201 single-photon emission computed tomography. The presence of ST-segment elevation in leads with Q waves was related to thallium reversibility at 4-hour redistribution imaging or after reinjection, to residual flow, as well as to wall motion abnormalities in the infarcted zone. ST-segment elevation in infarct-related leads was observed in 15 patients; 11 (73%) showed viability by thallium-201 in the infarcted zone. In patients without ST-segment elevation, viability was shown less frequently (33%, P < .05). Hypokinesis in infarcted segments was present in 60% of patients with ST-segment elevation and in 25% of patients without ST-segment elevation (.05 < P < .1). Finally, infarct-related artery was patent and/or collaterals were present in 10 patients with ST-segment elevation (67%) and in 4 patients without (33%, .05 < P < .1). In conclusion, ST-segment elevation during dobutamine infusion is a marker of residual viability in infarcted segments. |
| doi_str_mv | 10.1016/S0022-0736(05)80279-1 |
| format | Article |
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P ; PRASSOPOULOS, V ; KOSTAMIS, P ; MOULOPOULOS, S</creator><creatorcontrib>LEKAKIS, J. P ; PRASSOPOULOS, V ; KOSTAMIS, P ; MOULOPOULOS, S</creatorcontrib><description>The purpose of this study was to determine the significance of transient ST-segment elevation during dobutamine infusions in patients with healed Q wave myocardial infarction. Twenty-seven patients with previous Q wave myocardial infarction were studied prospectively with dobutamine-thallium-201 single-photon emission computed tomography. The presence of ST-segment elevation in leads with Q waves was related to thallium reversibility at 4-hour redistribution imaging or after reinjection, to residual flow, as well as to wall motion abnormalities in the infarcted zone. ST-segment elevation in infarct-related leads was observed in 15 patients; 11 (73%) showed viability by thallium-201 in the infarcted zone. In patients without ST-segment elevation, viability was shown less frequently (33%, P < .05). Hypokinesis in infarcted segments was present in 60% of patients with ST-segment elevation and in 25% of patients without ST-segment elevation (.05 < P < .1). Finally, infarct-related artery was patent and/or collaterals were present in 10 patients with ST-segment elevation (67%) and in 4 patients without (33%, .05 < P < .1). In conclusion, ST-segment elevation during dobutamine infusion is a marker of residual viability in infarcted segments.</description><identifier>ISSN: 0022-0736</identifier><identifier>EISSN: 1532-8430</identifier><identifier>DOI: 10.1016/S0022-0736(05)80279-1</identifier><identifier>PMID: 7616151</identifier><identifier>CODEN: JECAB4</identifier><language>eng</language><publisher>Orlando, FL: Churchill Livingstone</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Cardiology. Vascular system ; Coronary heart disease ; Dobutamine ; Electrocardiography ; Exercise Test ; Female ; Heart ; Humans ; Infusions, Intravenous ; Male ; Medical sciences ; Middle Aged ; Myocardial Infarction - diagnostic imaging ; Myocardial Infarction - physiopathology ; Thallium Radioisotopes ; Tomography, Emission-Computed, Single-Photon</subject><ispartof>Journal of electrocardiology, 1995-04, Vol.28 (2), p.91-97</ispartof><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3522299$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7616151$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LEKAKIS, J. P</creatorcontrib><creatorcontrib>PRASSOPOULOS, V</creatorcontrib><creatorcontrib>KOSTAMIS, P</creatorcontrib><creatorcontrib>MOULOPOULOS, S</creatorcontrib><title>Dobutamine-induced ST-segment elevation in patients with healed myocardial infarction: a marker of myocardial viability</title><title>Journal of electrocardiology</title><addtitle>J Electrocardiol</addtitle><description>The purpose of this study was to determine the significance of transient ST-segment elevation during dobutamine infusions in patients with healed Q wave myocardial infarction. Twenty-seven patients with previous Q wave myocardial infarction were studied prospectively with dobutamine-thallium-201 single-photon emission computed tomography. The presence of ST-segment elevation in leads with Q waves was related to thallium reversibility at 4-hour redistribution imaging or after reinjection, to residual flow, as well as to wall motion abnormalities in the infarcted zone. ST-segment elevation in infarct-related leads was observed in 15 patients; 11 (73%) showed viability by thallium-201 in the infarcted zone. In patients without ST-segment elevation, viability was shown less frequently (33%, P < .05). Hypokinesis in infarcted segments was present in 60% of patients with ST-segment elevation and in 25% of patients without ST-segment elevation (.05 < P < .1). Finally, infarct-related artery was patent and/or collaterals were present in 10 patients with ST-segment elevation (67%) and in 4 patients without (33%, .05 < P < .1). In conclusion, ST-segment elevation during dobutamine infusion is a marker of residual viability in infarcted segments.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Coronary heart disease</subject><subject>Dobutamine</subject><subject>Electrocardiography</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Heart</subject><subject>Humans</subject><subject>Infusions, Intravenous</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - diagnostic imaging</subject><subject>Myocardial Infarction - physiopathology</subject><subject>Thallium Radioisotopes</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><issn>0022-0736</issn><issn>1532-8430</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpN0EtLAzEQB_AgSq3Vj1DIQUQPq3nsbjbepD6h4KH1vMwmsxrdR93stvTbG7EUTxkyP4aZPyFTzq454-nNgjEhIqZkesmSq4wJpSN-QMY8kSLKYskOyXhPjsmJ95-MMS2UGJGRSnnKEz4mm_u2GHqoXYORa-xg0NLFMvL4XmPTU6xwDb1rG-oaugpV-PR04_oP-oFQBVxvWwOddVAFUkJnfvUtBVpD94Udbcv_ZO2gcJXrt6fkqITK49nunZC3x4fl7Dmavz69zO7m0UrIpI-44QpQZ2Fzo2OrQIu0AJ1xELw0mVUYcy5LIxmmFlihUPMQRClsYbU2Sk7Ixd_cVdd-D-j7vHbeYFVBg-3gc6XikKaQAU53cChqtPmqc-GCbb5LKvTPd33wBqqyg8Y4v2cyEUJoLX8Aw6p6Xw</recordid><startdate>19950401</startdate><enddate>19950401</enddate><creator>LEKAKIS, J. P</creator><creator>PRASSOPOULOS, V</creator><creator>KOSTAMIS, P</creator><creator>MOULOPOULOS, S</creator><general>Churchill Livingstone</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19950401</creationdate><title>Dobutamine-induced ST-segment elevation in patients with healed myocardial infarction: a marker of myocardial viability</title><author>LEKAKIS, J. P ; PRASSOPOULOS, V ; KOSTAMIS, P ; MOULOPOULOS, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p235t-1c17ae98000c94d7a926ba981a21fc8d7e4113fc30e6da0b7e91279f2dbd99c73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Coronary heart disease</topic><topic>Dobutamine</topic><topic>Electrocardiography</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Heart</topic><topic>Humans</topic><topic>Infusions, Intravenous</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - diagnostic imaging</topic><topic>Myocardial Infarction - physiopathology</topic><topic>Thallium Radioisotopes</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LEKAKIS, J. P</creatorcontrib><creatorcontrib>PRASSOPOULOS, V</creatorcontrib><creatorcontrib>KOSTAMIS, P</creatorcontrib><creatorcontrib>MOULOPOULOS, S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of electrocardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LEKAKIS, J. P</au><au>PRASSOPOULOS, V</au><au>KOSTAMIS, P</au><au>MOULOPOULOS, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dobutamine-induced ST-segment elevation in patients with healed myocardial infarction: a marker of myocardial viability</atitle><jtitle>Journal of electrocardiology</jtitle><addtitle>J Electrocardiol</addtitle><date>1995-04-01</date><risdate>1995</risdate><volume>28</volume><issue>2</issue><spage>91</spage><epage>97</epage><pages>91-97</pages><issn>0022-0736</issn><eissn>1532-8430</eissn><coden>JECAB4</coden><abstract>The purpose of this study was to determine the significance of transient ST-segment elevation during dobutamine infusions in patients with healed Q wave myocardial infarction. Twenty-seven patients with previous Q wave myocardial infarction were studied prospectively with dobutamine-thallium-201 single-photon emission computed tomography. The presence of ST-segment elevation in leads with Q waves was related to thallium reversibility at 4-hour redistribution imaging or after reinjection, to residual flow, as well as to wall motion abnormalities in the infarcted zone. ST-segment elevation in infarct-related leads was observed in 15 patients; 11 (73%) showed viability by thallium-201 in the infarcted zone. In patients without ST-segment elevation, viability was shown less frequently (33%, P < .05). Hypokinesis in infarcted segments was present in 60% of patients with ST-segment elevation and in 25% of patients without ST-segment elevation (.05 < P < .1). Finally, infarct-related artery was patent and/or collaterals were present in 10 patients with ST-segment elevation (67%) and in 4 patients without (33%, .05 < P < .1). In conclusion, ST-segment elevation during dobutamine infusion is a marker of residual viability in infarcted segments.</abstract><cop>Orlando, FL</cop><cop>Philadelphia, PA</cop><pub>Churchill Livingstone</pub><pmid>7616151</pmid><doi>10.1016/S0022-0736(05)80279-1</doi><tpages>7</tpages></addata></record> |
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| ispartof | Journal of electrocardiology, 1995-04, Vol.28 (2), p.91-97 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Aged Biological and medical sciences Cardiology. Vascular system Coronary heart disease Dobutamine Electrocardiography Exercise Test Female Heart Humans Infusions, Intravenous Male Medical sciences Middle Aged Myocardial Infarction - diagnostic imaging Myocardial Infarction - physiopathology Thallium Radioisotopes Tomography, Emission-Computed, Single-Photon |
| title | Dobutamine-induced ST-segment elevation in patients with healed myocardial infarction: a marker of myocardial viability |
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