A comparative histological study of wound healing following Nd:YAG laser with different energy parameters and conventional surgical incision in rat skin
Wound healing following the use of Nd:YAG laser with different frequencies and energy parameters (20 pps and 1.75 W/30 pps and 3.0 W), and the conventional scalpel incision were studied over a period of 4, 7, 14, 21, and 28 days in the rat skin. The low-energy laser wounds could not be significantly...
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Veröffentlicht in: | Journal of clinical laser medicine & surgery 1995-02, Vol.13 (1), p.11-16 |
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description | Wound healing following the use of Nd:YAG laser with different frequencies and energy parameters (20 pps and 1.75 W/30 pps and 3.0 W), and the conventional scalpel incision were studied over a period of 4, 7, 14, 21, and 28 days in the rat skin. The low-energy laser wounds could not be significantly differentiated from the conventional incisions although less damage and inflammatory reaction, increased matrix production, and only a little wound contraction could be demonstrated. In the high-energy lased tissues extensive damage and an increased inflammatory reaction were present. The low-energy Nd:YAG and scalpel incisions established a normal wound healing without scar tissue formation compared to the high-energy Nd:YAG, where the necrosis was higher. |
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The low-energy laser wounds could not be significantly differentiated from the conventional incisions although less damage and inflammatory reaction, increased matrix production, and only a little wound contraction could be demonstrated. In the high-energy lased tissues extensive damage and an increased inflammatory reaction were present. 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The low-energy laser wounds could not be significantly differentiated from the conventional incisions although less damage and inflammatory reaction, increased matrix production, and only a little wound contraction could be demonstrated. In the high-energy lased tissues extensive damage and an increased inflammatory reaction were present. The low-energy Nd:YAG and scalpel incisions established a normal wound healing without scar tissue formation compared to the high-energy Nd:YAG, where the necrosis was higher.</description><subject>Animals</subject><subject>Dermatologic Surgical Procedures</subject><subject>Health technology assessment</subject><subject>Laser Therapy</subject><subject>Male</subject><subject>Neodymium</subject><subject>Rats</subject><subject>Skin - pathology</subject><subject>Wound Healing - physiology</subject><subject>Wound Healing - radiation effects</subject><issn>1044-5471</issn><issn>1557-8089</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkUFv1DAQha2Kqi2FK0fkE7eEcRLHCbdVVQpSRS9w4GR57fGuwbEXO-lq_wk_F0fbA6d5mvf82fIj5B2DmsEwftR-qtk48pq1NWMX5IZxLqqhWK-Khq6reCfYNXmd8y8A4KPorsg1A8aB98MN-buhOk4HldTsnpHuXZ6jjzunlad5XsyJRkuPcQmG7lF5F3bURu_jcVXfzKefmwfqVcZEj27eU-OsxYRhphgw7U50JU84Y8pUFYaO4bm4LoaVv6TzRS5ol8uuCFoeQvNvF96QS6t8xrcv85b8-Hz__e5L9fj08PVu81jpBvq5Gk0ncMs7I5p-O-AA2I1GNYorMWgwLefWWgPImn5kQgNnChoYoOWD3fbQt7fkw5l7SPHPgnmWk8savVcB45KlEB0IYGMJ1uegTjHnhFYekptUOkkGcu1Cli7k2oVkrWSsHHj_Ql62E5r_4ufPb_8Bbv-Idg</recordid><startdate>199502</startdate><enddate>199502</enddate><creator>Romanos, G E</creator><creator>Pelekanos, S</creator><creator>Strub, J R</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199502</creationdate><title>A comparative histological study of wound healing following Nd:YAG laser with different energy parameters and conventional surgical incision in rat skin</title><author>Romanos, G E ; Pelekanos, S ; Strub, J R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c206t-9d47eb54d726b8e80e49da2a5a78c0d355fffd0e126917c051a02080358fb6063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Animals</topic><topic>Dermatologic Surgical Procedures</topic><topic>Health technology assessment</topic><topic>Laser Therapy</topic><topic>Male</topic><topic>Neodymium</topic><topic>Rats</topic><topic>Skin - pathology</topic><topic>Wound Healing - physiology</topic><topic>Wound Healing - radiation effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Romanos, G E</creatorcontrib><creatorcontrib>Pelekanos, S</creatorcontrib><creatorcontrib>Strub, J R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical laser medicine & surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Romanos, G E</au><au>Pelekanos, S</au><au>Strub, J R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparative histological study of wound healing following Nd:YAG laser with different energy parameters and conventional surgical incision in rat skin</atitle><jtitle>Journal of clinical laser medicine & surgery</jtitle><addtitle>J Clin Laser Med Surg</addtitle><date>1995-02</date><risdate>1995</risdate><volume>13</volume><issue>1</issue><spage>11</spage><epage>16</epage><pages>11-16</pages><issn>1044-5471</issn><eissn>1557-8089</eissn><abstract>Wound healing following the use of Nd:YAG laser with different frequencies and energy parameters (20 pps and 1.75 W/30 pps and 3.0 W), and the conventional scalpel incision were studied over a period of 4, 7, 14, 21, and 28 days in the rat skin. The low-energy laser wounds could not be significantly differentiated from the conventional incisions although less damage and inflammatory reaction, increased matrix production, and only a little wound contraction could be demonstrated. In the high-energy lased tissues extensive damage and an increased inflammatory reaction were present. The low-energy Nd:YAG and scalpel incisions established a normal wound healing without scar tissue formation compared to the high-energy Nd:YAG, where the necrosis was higher.</abstract><cop>United States</cop><pmid>10150568</pmid><doi>10.1089/clm.1995.13.11</doi><tpages>6</tpages></addata></record> |
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subjects | Animals Dermatologic Surgical Procedures Health technology assessment Laser Therapy Male Neodymium Rats Skin - pathology Wound Healing - physiology Wound Healing - radiation effects |
title | A comparative histological study of wound healing following Nd:YAG laser with different energy parameters and conventional surgical incision in rat skin |
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