Effect of acute and chronic treatment with the angiotensin II subtype 1 receptor antagonist EXP 3174 on baroreflex function in conscious spontaneously hypertensive rats

To determine whether the angiotensin II subtype 1 (AT1) receptor antagonist EXP 3174 can modify the baroreceptor-heart rate reflex in conscious rats. EXP 3174 was given acutely, both peripherally and centrally, as well as chronically to spontaneously hypertensive rats (SHR), and baroreflex function...

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Veröffentlicht in:	Journal of hypertension 1995-02, Vol.13 (2), p.219-225
Hauptverfasser:	BARTHOLOMEUSZ, B, WIDDOP, R. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin Receptor Antagonists Animals Antihypertensive agents Baroreflex - drug effects Biological and medical sciences Blood Pressure Cardiovascular system Heart Rate Hypertension - drug therapy Hypertension - metabolism Hypertension - physiopathology Imidazoles - pharmacology Losartan Male Medical sciences Pharmacology. Drug treatments Rats Rats, Inbred SHR Rats, Inbred WKY Receptors, Angiotensin - physiology Tetrazoles - pharmacology
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