Allogeneic sibling umbilical-cord-blood transplantation in children with malignant and non-malignant disease

Allogeneic bone marrow transplantation is limited by the availability of suitable marrow donors and risk of graft-versus-host disease (GVHD) and opportunistic infection. In an attempt to ameliorate these limitations, umbilical cord blood has been postulated as an alternative source of allogeneic hae...

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Veröffentlicht in:	The Lancet (British edition) 1995-07, Vol.346 (8969), p.214-219
Hauptverfasser:	Wagner, JohnE, Steinbuch, Michael, Kernan, NancyA, Broxmayer, HalE, Gluckman, Eliane
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood & organ donations Bone marrow Bone marrow, stem cells transplantation. Graft versus host reaction Child Child, Preschool Children & youth Chronic Disease Disease Female Fetal Blood - cytology Graft Survival Graft vs Host Disease - etiology Hematologic Diseases - mortality Hematologic Diseases - therapy Hematopoietic Stem Cell Transplantation - adverse effects Histocompatibility Testing Humans Infant Male Medical research Medical sciences Metabolic Diseases - mortality Metabolic Diseases - therapy Metabolic disorders Neuroblastoma - mortality Neuroblastoma - therapy Probability Sibling Relations Siblings Stem cells Survival Rate Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation, Homologous
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