The role of nitric oxide in modulating brain activity and blood flow during seizure

The role played by nitric oxide (NO) in modulating seizure activity and cerebral blood flow (CBF) during seizures was investigated in rats. Seizures were induced with bicuculline (a GAB A antagonist, 1.2 mg kg, i.v.). Each animal was subjected to an initial bicuculline-induced seizure followed by tr...

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Veröffentlicht in:	Neuroreport 1995-04, Vol.6 (6), p.921-924
Hauptverfasser:	Theard, M Angele, Baughman, Verna L, Wang, Qiong, Pelligrino, Dale A, Albrecht, Ronald F
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Oxidoreductases - antagonists & inhibitors Animals Anticonvulsants. Antiepileptics. Antiparkinson agents Arginine - analogs & derivatives Arginine - pharmacology Bicuculline - pharmacology Biological and medical sciences Brain - physiopathology Cerebrovascular Circulation - drug effects Cerebrovascular Circulation - physiology Electroencephalography Male Medical sciences Neuropharmacology Nitric Oxide - antagonists & inhibitors Nitric Oxide - physiology Nitric Oxide Synthase Nitroarginine Pharmacology. Drug treatments Rats Rats, Wistar Seizures - physiopathology
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