Pleurotus Fruiting Bodies Contain the Inhibitor of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase—Lovastatin
Gunde-Cimerman, N., and Cimerman, A. 1995. Pleurotus fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin. Experimental Mycology 19, 1-6. In the fruiting bodies of the fungus Pleurotus ostreatus, also called the oyster mushroom, we found a competitive i...
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| Veröffentlicht in: | Experimental mycology 1995-03, Vol.19 (1), p.1-6 |
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| creator | Gunde-Cimerman, Nina Cimerman, Aleksa |
| description | Gunde-Cimerman, N., and Cimerman, A. 1995.
Pleurotus fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin.
Experimental Mycology 19, 1-6. In the fruiting bodies of the fungus
Pleurotus ostreatus, also called the oyster mushroom, we found a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase—lovastatin. The appearance of the inhibitor during the development of fruiting bodies was followed and lovastatin determined in the vegetative mycelium, in the primordia, as well as in different parts of sporocarps of different sizes. Less lovastatin was found in stipes as compared to pili or in mature stages in the lamellae and basidiospores. |
| doi_str_mv | 10.1006/emyc.1995.1001 |
| format | Article |
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Pleurotus fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin.
Experimental Mycology 19, 1-6. In the fruiting bodies of the fungus
Pleurotus ostreatus, also called the oyster mushroom, we found a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase—lovastatin. The appearance of the inhibitor during the development of fruiting bodies was followed and lovastatin determined in the vegetative mycelium, in the primordia, as well as in different parts of sporocarps of different sizes. Less lovastatin was found in stipes as compared to pili or in mature stages in the lamellae and basidiospores.</description><identifier>ISSN: 0147-5975</identifier><identifier>EISSN: 1878-4399</identifier><identifier>DOI: 10.1006/emyc.1995.1001</identifier><identifier>PMID: 7614366</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Cell Extracts ; champignon comestible ; Chromatography, High Pressure Liquid ; edible fungi ; enzyme inhibitors ; Hydroxymethylglutaryl CoA Reductases ; inhibidores de enzimas ; inhibiteur d' enzyme ; Lovastatin - analysis ; oxidoreductases ; oxidorreductasas ; oxydoreductase ; pleurotus ; Pleurotus ostreatus ; Pleurotus ostreatus; sporocarp; inhibition of HMG CoA reductase; lovastatin ; Polyporaceae - chemistry ; Polyporaceae - growth & development ; protein synthesis ; proteinas ; proteine ; proteins ; setas comestibles ; sintesis de proteinas ; Spores, Fungal - chemistry ; synthese proteique ; Tissue Distribution</subject><ispartof>Experimental mycology, 1995-03, Vol.19 (1), p.1-6</ispartof><rights>1995 Academic Press</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-35d579eceff5d9781a0905d479bd16015dd6f77d739673078079fbccb62888923</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7614366$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gunde-Cimerman, Nina</creatorcontrib><creatorcontrib>Cimerman, Aleksa</creatorcontrib><creatorcontrib>Agricultural Research Corporation, Wad Medani (Sudan). Shambat Research Station</creatorcontrib><creatorcontrib>National Institute of Chemistry, Slovenia</creatorcontrib><title>Pleurotus Fruiting Bodies Contain the Inhibitor of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase—Lovastatin</title><title>Experimental mycology</title><addtitle>Exp Mycol</addtitle><description>Gunde-Cimerman, N., and Cimerman, A. 1995.
Pleurotus fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin.
Experimental Mycology 19, 1-6. In the fruiting bodies of the fungus
Pleurotus ostreatus, also called the oyster mushroom, we found a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase—lovastatin. The appearance of the inhibitor during the development of fruiting bodies was followed and lovastatin determined in the vegetative mycelium, in the primordia, as well as in different parts of sporocarps of different sizes. Less lovastatin was found in stipes as compared to pili or in mature stages in the lamellae and basidiospores.</description><subject>Cell Extracts</subject><subject>champignon comestible</subject><subject>Chromatography, High Pressure Liquid</subject><subject>edible fungi</subject><subject>enzyme inhibitors</subject><subject>Hydroxymethylglutaryl CoA Reductases</subject><subject>inhibidores de enzimas</subject><subject>inhibiteur d' enzyme</subject><subject>Lovastatin - analysis</subject><subject>oxidoreductases</subject><subject>oxidorreductasas</subject><subject>oxydoreductase</subject><subject>pleurotus</subject><subject>Pleurotus ostreatus</subject><subject>Pleurotus ostreatus; sporocarp; inhibition of HMG CoA reductase; lovastatin</subject><subject>Polyporaceae - chemistry</subject><subject>Polyporaceae - growth & development</subject><subject>protein synthesis</subject><subject>proteinas</subject><subject>proteine</subject><subject>proteins</subject><subject>setas comestibles</subject><subject>sintesis de proteinas</subject><subject>Spores, Fungal - chemistry</subject><subject>synthese proteique</subject><subject>Tissue Distribution</subject><issn>0147-5975</issn><issn>1878-4399</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc9u1DAQxi0EKkvhyg2UEzcvdh3_O5YVpZUWtQJ6thx7smuUxMV2qoZTH4In5ElItCtuiNNoNL_vG818CL2mZE0JEe-hn9yaas2Xlj5BK6qkwjXT-ilaEVpLzLXkz9GLnL8TQjQT5ASdSEFrJsQKxZsOxhTLmKuLNIYShl31IfoAudrEodgwVGUP1dWwD00oMVWxrRi-nHyKDxNm-DOU_dTturHYNHV4E2H4OfVQnVdfwI-u2Ay_H39t473Nxc7uL9Gz1nYZXh3rKbq9-Phtc4m315-uNudb7JhmBTPuudTgoG2511JRSzThvpa68VQQyr0XrZReMi0kI1IRqdvGuUacKaX0GTtF7w6-dyn-GCEX04fsoOvsAHHMRs5KRXX9X5AKqYQiC7g-gC7FnBO05i6Ffr7aUGKWKMwShVmiWFo6C94cncemB_8XP_5-nr89zFsbjd2lkM3t11kuCKkJ42oG1AGA-VH3AZLJLsDgwIcErhgfw792_wGbUKKe</recordid><startdate>19950301</startdate><enddate>19950301</enddate><creator>Gunde-Cimerman, Nina</creator><creator>Cimerman, Aleksa</creator><general>Elsevier Inc</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19950301</creationdate><title>Pleurotus Fruiting Bodies Contain the Inhibitor of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase—Lovastatin</title><author>Gunde-Cimerman, Nina ; Cimerman, Aleksa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c393t-35d579eceff5d9781a0905d479bd16015dd6f77d739673078079fbccb62888923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Cell Extracts</topic><topic>champignon comestible</topic><topic>Chromatography, High Pressure Liquid</topic><topic>edible fungi</topic><topic>enzyme inhibitors</topic><topic>Hydroxymethylglutaryl CoA Reductases</topic><topic>inhibidores de enzimas</topic><topic>inhibiteur d' enzyme</topic><topic>Lovastatin - analysis</topic><topic>oxidoreductases</topic><topic>oxidorreductasas</topic><topic>oxydoreductase</topic><topic>pleurotus</topic><topic>Pleurotus ostreatus</topic><topic>Pleurotus ostreatus; sporocarp; inhibition of HMG CoA reductase; lovastatin</topic><topic>Polyporaceae - chemistry</topic><topic>Polyporaceae - growth & development</topic><topic>protein synthesis</topic><topic>proteinas</topic><topic>proteine</topic><topic>proteins</topic><topic>setas comestibles</topic><topic>sintesis de proteinas</topic><topic>Spores, Fungal - chemistry</topic><topic>synthese proteique</topic><topic>Tissue Distribution</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gunde-Cimerman, Nina</creatorcontrib><creatorcontrib>Cimerman, Aleksa</creatorcontrib><creatorcontrib>Agricultural Research Corporation, Wad Medani (Sudan). Shambat Research Station</creatorcontrib><creatorcontrib>National Institute of Chemistry, Slovenia</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental mycology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gunde-Cimerman, Nina</au><au>Cimerman, Aleksa</au><aucorp>Agricultural Research Corporation, Wad Medani (Sudan). Shambat Research Station</aucorp><aucorp>National Institute of Chemistry, Slovenia</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pleurotus Fruiting Bodies Contain the Inhibitor of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase—Lovastatin</atitle><jtitle>Experimental mycology</jtitle><addtitle>Exp Mycol</addtitle><date>1995-03-01</date><risdate>1995</risdate><volume>19</volume><issue>1</issue><spage>1</spage><epage>6</epage><pages>1-6</pages><issn>0147-5975</issn><eissn>1878-4399</eissn><abstract>Gunde-Cimerman, N., and Cimerman, A. 1995.
Pleurotus fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin.
Experimental Mycology 19, 1-6. In the fruiting bodies of the fungus
Pleurotus ostreatus, also called the oyster mushroom, we found a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase—lovastatin. The appearance of the inhibitor during the development of fruiting bodies was followed and lovastatin determined in the vegetative mycelium, in the primordia, as well as in different parts of sporocarps of different sizes. Less lovastatin was found in stipes as compared to pili or in mature stages in the lamellae and basidiospores.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7614366</pmid><doi>10.1006/emyc.1995.1001</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Cell Extracts champignon comestible Chromatography, High Pressure Liquid edible fungi enzyme inhibitors Hydroxymethylglutaryl CoA Reductases inhibidores de enzimas inhibiteur d' enzyme Lovastatin - analysis oxidoreductases oxidorreductasas oxydoreductase pleurotus Pleurotus ostreatus Pleurotus ostreatus sporocarp inhibition of HMG CoA reductase lovastatin Polyporaceae - chemistry Polyporaceae - growth & development protein synthesis proteinas proteine proteins setas comestibles sintesis de proteinas Spores, Fungal - chemistry synthese proteique Tissue Distribution |
| title | Pleurotus Fruiting Bodies Contain the Inhibitor of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase—Lovastatin |
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