Interventions to treat malnutrition in dialysis patients: The role of the dose of dialysis, intradialytic parenteral nutrition, and growth hormone
Protein and calorie malnutrition often starts before initiation of dialysis, and reflects the anorexia and the catabolic state of chronic renal failure. In the face of inadequate dialysis, which perpetuates the uremic state, malnutrition often worsens. Several studies, though not all, suggest that o...
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| Veröffentlicht in: | American journal of kidney diseases 1995-07, Vol.26 (1), p.256-265 |
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| creator | Ikizler, T.Alp Wingard, Rebecca L. Hakim, Raymond M. |
| description | Protein and calorie malnutrition often starts before initiation of dialysis, and reflects the anorexia and the catabolic state of chronic renal failure. In the face of inadequate dialysis, which perpetuates the uremic state, malnutrition often worsens. Several studies, though not all, suggest that optimal dialysis improves nutritional status of dialysis patients. Such optimal dialysis now must include the use of biocompatible membranes to deliver Kt/V > 1.4 (urea reduction ratio > 65%). Additional interventions can include the use of enteral or intravenous hyperalimentation, and recombinant growth factors such as growth hormone or insulin-like growth factor-1. Importantly, studies to document the improvement in the morbidity and mortality of patients with these interventions are still needed and require large multicenter trials. |
| doi_str_mv | 10.1016/0272-6386(95)90181-7 |
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In the face of inadequate dialysis, which perpetuates the uremic state, malnutrition often worsens. Several studies, though not all, suggest that optimal dialysis improves nutritional status of dialysis patients. Such optimal dialysis now must include the use of biocompatible membranes to deliver Kt/V > 1.4 (urea reduction ratio > 65%). Additional interventions can include the use of enteral or intravenous hyperalimentation, and recombinant growth factors such as growth hormone or insulin-like growth factor-1. 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Renal failure ; Nutrition Disorders - drug therapy ; Nutrition Disorders - etiology ; Nutrition Disorders - therapy ; Parenteral Nutrition ; Peritoneal Dialysis, Continuous Ambulatory - adverse effects ; Peritoneal Dialysis, Continuous Ambulatory - instrumentation ; Peritoneal Dialysis, Continuous Ambulatory - methods ; Recombinant Proteins - therapeutic use ; Renal Dialysis - adverse effects ; Renal Dialysis - instrumentation ; Renal Dialysis - methods ; Renal failure</subject><ispartof>American journal of kidney diseases, 1995-07, Vol.26 (1), p.256-265</ispartof><rights>1995</rights><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-d27ac352a8d09ae1423875d0b643ca7e855250da75bf757e4af7df79493d17253</citedby><cites>FETCH-LOGICAL-c386t-d27ac352a8d09ae1423875d0b643ca7e855250da75bf757e4af7df79493d17253</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0272-6386(95)90181-7$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,780,784,789,790,3550,23930,23931,25140,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3639634$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7611260$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ikizler, T.Alp</creatorcontrib><creatorcontrib>Wingard, Rebecca L.</creatorcontrib><creatorcontrib>Hakim, Raymond M.</creatorcontrib><title>Interventions to treat malnutrition in dialysis patients: The role of the dose of dialysis, intradialytic parenteral nutrition, and growth hormone</title><title>American journal of kidney diseases</title><addtitle>Am J Kidney Dis</addtitle><description>Protein and calorie malnutrition often starts before initiation of dialysis, and reflects the anorexia and the catabolic state of chronic renal failure. In the face of inadequate dialysis, which perpetuates the uremic state, malnutrition often worsens. Several studies, though not all, suggest that optimal dialysis improves nutritional status of dialysis patients. Such optimal dialysis now must include the use of biocompatible membranes to deliver Kt/V > 1.4 (urea reduction ratio > 65%). Additional interventions can include the use of enteral or intravenous hyperalimentation, and recombinant growth factors such as growth hormone or insulin-like growth factor-1. Importantly, studies to document the improvement in the morbidity and mortality of patients with these interventions are still needed and require large multicenter trials.</description><subject>Biological and medical sciences</subject><subject>Growth Hormone - therapeutic use</subject><subject>Humans</subject><subject>Insulin-Like Growth Factor I - therapeutic use</subject><subject>Kidney Failure, Chronic - complications</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Medical sciences</subject><subject>Membranes, Artificial</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Nephropathies. Renovascular diseases. Renal failure</subject><subject>Nutrition Disorders - drug therapy</subject><subject>Nutrition Disorders - etiology</subject><subject>Nutrition Disorders - therapy</subject><subject>Parenteral Nutrition</subject><subject>Peritoneal Dialysis, Continuous Ambulatory - adverse effects</subject><subject>Peritoneal Dialysis, Continuous Ambulatory - instrumentation</subject><subject>Peritoneal Dialysis, Continuous Ambulatory - methods</subject><subject>Recombinant Proteins - therapeutic use</subject><subject>Renal Dialysis - adverse effects</subject><subject>Renal Dialysis - instrumentation</subject><subject>Renal Dialysis - methods</subject><subject>Renal failure</subject><issn>0272-6386</issn><issn>1523-6838</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc2OFCEUhYnRjD2jb6AJC2PGZEqhKKBwYWIm_kwyiZtxTW7DLRtTVbRAj5nX8ImlutteuuLC_c4BziXkBWdvOePqHWt12yjRq0sj3xjGe97oR2TFZSsa1Yv-MVmdkKfkPOefjDEjlDojZ1px3iq2In9u5oLpHucS4pxpibQkhEInGOddSWE5pmGmPsD4kEOmWyih0vk9vdsgTXFEGgdaau1j3tf_0KuqKwn22xJcVSZcLoORnqyvKMye_kjxd9nQTUxTnPEZeTLAmPH5cb0g3z9_urv-2tx--3Jz_fG2cfVDpfGtBidkC71nBpB3rei19GytOuFAYy9lK5kHLdeDlho7GLQftOmM8Fy3UlyQ1wffbYq_dpiLnUJ2OI4wY9xlq7UwuutVBbsD6FLMOeFgtylMkB4sZ3YZhV1ytkvO1ki7H4XVVfby6L9bT-hPomP2tf_q2IfsYBwSzC7kEyaUMEp0FftwwLBmcR8w2ezqBBz6kNAV62P4_zv-AncyqAk</recordid><startdate>19950701</startdate><enddate>19950701</enddate><creator>Ikizler, T.Alp</creator><creator>Wingard, Rebecca L.</creator><creator>Hakim, Raymond M.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19950701</creationdate><title>Interventions to treat malnutrition in dialysis patients: The role of the dose of dialysis, intradialytic parenteral nutrition, and growth hormone</title><author>Ikizler, T.Alp ; Wingard, Rebecca L. ; Hakim, Raymond M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-d27ac352a8d09ae1423875d0b643ca7e855250da75bf757e4af7df79493d17253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Biological and medical sciences</topic><topic>Growth Hormone - therapeutic use</topic><topic>Humans</topic><topic>Insulin-Like Growth Factor I - therapeutic use</topic><topic>Kidney Failure, Chronic - complications</topic><topic>Kidney Failure, Chronic - therapy</topic><topic>Medical sciences</topic><topic>Membranes, Artificial</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Nephropathies. Renovascular diseases. Renal failure</topic><topic>Nutrition Disorders - drug therapy</topic><topic>Nutrition Disorders - etiology</topic><topic>Nutrition Disorders - therapy</topic><topic>Parenteral Nutrition</topic><topic>Peritoneal Dialysis, Continuous Ambulatory - adverse effects</topic><topic>Peritoneal Dialysis, Continuous Ambulatory - instrumentation</topic><topic>Peritoneal Dialysis, Continuous Ambulatory - methods</topic><topic>Recombinant Proteins - therapeutic use</topic><topic>Renal Dialysis - adverse effects</topic><topic>Renal Dialysis - instrumentation</topic><topic>Renal Dialysis - methods</topic><topic>Renal failure</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ikizler, T.Alp</creatorcontrib><creatorcontrib>Wingard, Rebecca L.</creatorcontrib><creatorcontrib>Hakim, Raymond M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of kidney diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ikizler, T.Alp</au><au>Wingard, Rebecca L.</au><au>Hakim, Raymond M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Interventions to treat malnutrition in dialysis patients: The role of the dose of dialysis, intradialytic parenteral nutrition, and growth hormone</atitle><jtitle>American journal of kidney diseases</jtitle><addtitle>Am J Kidney Dis</addtitle><date>1995-07-01</date><risdate>1995</risdate><volume>26</volume><issue>1</issue><spage>256</spage><epage>265</epage><pages>256-265</pages><issn>0272-6386</issn><eissn>1523-6838</eissn><abstract>Protein and calorie malnutrition often starts before initiation of dialysis, and reflects the anorexia and the catabolic state of chronic renal failure. In the face of inadequate dialysis, which perpetuates the uremic state, malnutrition often worsens. Several studies, though not all, suggest that optimal dialysis improves nutritional status of dialysis patients. Such optimal dialysis now must include the use of biocompatible membranes to deliver Kt/V > 1.4 (urea reduction ratio > 65%). Additional interventions can include the use of enteral or intravenous hyperalimentation, and recombinant growth factors such as growth hormone or insulin-like growth factor-1. Importantly, studies to document the improvement in the morbidity and mortality of patients with these interventions are still needed and require large multicenter trials.</abstract><cop>Orlando, FL</cop><pub>Elsevier Inc</pub><pmid>7611260</pmid><doi>10.1016/0272-6386(95)90181-7</doi><tpages>10</tpages></addata></record> |
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| subjects | Biological and medical sciences Growth Hormone - therapeutic use Humans Insulin-Like Growth Factor I - therapeutic use Kidney Failure, Chronic - complications Kidney Failure, Chronic - therapy Medical sciences Membranes, Artificial Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Nutrition Disorders - drug therapy Nutrition Disorders - etiology Nutrition Disorders - therapy Parenteral Nutrition Peritoneal Dialysis, Continuous Ambulatory - adverse effects Peritoneal Dialysis, Continuous Ambulatory - instrumentation Peritoneal Dialysis, Continuous Ambulatory - methods Recombinant Proteins - therapeutic use Renal Dialysis - adverse effects Renal Dialysis - instrumentation Renal Dialysis - methods Renal failure |
| title | Interventions to treat malnutrition in dialysis patients: The role of the dose of dialysis, intradialytic parenteral nutrition, and growth hormone |
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