The impact of heparin concentration and activated clotting time monitoring on blood conservation: A prospective, randomized evaluation in patients undergoing cardiac operation

A whole blood hemostasis system (Hepcon) provides both activated clotting time and accurate whole blood heparin concentration measurements via an automated protamine titration method. This study was designed to prospectively evaluate the impact of heparin and protamine administration using this syst...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 1995-07, Vol.110 (1), p.46-54
Hauptverfasser:	Despotis, G. J, Joist, J. H, Hogue, C. W., Jr, Alsoufiev, A, Kater, K, Goodnough, L. T, Santoro, S. A, Spitznagel, E, Rosenblum, M, Lappas, D. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Blood Coagulation Tests - instrumentation Blood Loss, Surgical - prevention & control Blood Transfusion - statistics & numerical data Blood. Blood coagulation. Reticuloendothelial system Cardiopulmonary Bypass - methods Chi-Square Distribution Female Heparin - administration & dosage Heparin - blood Humans Male Medical sciences Middle Aged Monitoring, Physiologic - instrumentation Pharmacology. Drug treatments Prospective Studies Protamines - administration & dosage Protamines - analysis Whole Blood Coagulation Time
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